外出打工史与肺结核病发病联系的病例对照研究  

A CASE-CONTROL STUDY ON ASSOCIATION THAT HISTORY OF OUT-MIGRANT FOR WORK WITH INCIDENCE OF PULMONARY TUBERCULOSIS FOR FARMERS

作　　者：周刚[1] 王国杰[1] Adrian Sleigh 冯石献[1] 王盟[1] Sukhan Jackson 张柯[1] 王卫峰[1] 焦晓磊[1] 刘禧礼[1] 

机构地区：[1]河南省疾病预防控制中心,郑州450003 [2]澳大利亚国立大学流行病学与人群健康国家中心 [3]澳大利亚昆士兰大学经济学院

出　　处：《现代预防医学》2007年第10期1801-1804,1806,共5页Modern Preventive Medicine

基　　金：UNDP[WB]WHOTDR资助项目(A10166);河南省科技发展计划国际合作资助项目(034664004)

摘　　要：[目的]探讨外出打工史与肺结核病发病的联系。[方法]采用病例对照研究,从结核病防治机构发现的肺结核人中选取160例25～60岁的涂阳肺结核病人作为病例,每个病例选取2名作为对照。[结果]160名肺结核病人与320名对照者有外出打工史的分别占46.9%、29.4%,二者差异具有统计学意义,OR值为2.4;近3年外出打工史分别占31.9%、17.8%,二者差异有统计学意义,OR值为2.4。采用多因素分析,控制了混杂因素后,外出打工史、近3年外出打工史的OR值仍为2.2、2.0。男性外出打工史、近3年外出打工史与肺结核发病显著性关联,其校正后的OR值分别为2.7、2.4。进一步采用多因素logistic回归模型分析,外出打工的工作场所条件不舒适、每天工作时间超过8h、每周没有休息日的OR值与95%CI分别为4.8(1.7～13.8)、4.9(1.5～16.0)、4.7(1.4～15.4)。[结论]男性外出打工与肺结核发病密切相联系,外出打工工作场所条件差,工作时间较长、每周没有休息日是农民外出打工发生肺结核的重要危险因素;女性外出打工与肺结核有无联系尚需进一步研究。ObjectiveTo explore association that history of out-migrant for work with incidence of pulmonary tuberculosis for farmers.MethodsA case-control study was conducted.160 new smear positive TB patients were selected as cases,who aged from 25 to 60,were notified and registered by county＇s anti-TB institutes;and 320 healthy persons were selected as controls.ResultsThe percentage of TB patients with history of out-migrant for work were 46.9% and 29.4% respectively,there was significant difference between the two and the value of OR was 2.4; and that for subjects with history of out -migrated for work during the recent 3 years were 31：9% and 17.8%, respectively and there was obvious difference, the Odds Ratio equlled to 2.4. Multivariate analysis after controlling confounding factors showed Odds Ratio equalled to 2.2 and 2.0 respectively for patients with history of out＇migrant for work and history of out＇migrant for work during the recent 3 years. History of out-migrant for work and history of out-migrant for work during the recent 3 years in male was significantly associated with TB, Odds Ratio equalled to 2i7 and 2.4 respectiVely after correction. After model of multivariate logistic regression were used for analysis , Odds Ratio and 95%CI of poor workplace condition, work hour more than 8 hours each day, not having a resi day each week were 4.8 （17-13.8）, 4.9 （1.5-16.0）. 417 （1.4-15.4） respectively. [Conclusions] History Of out-migrant for work in male is significandy assoeiated with TB, poor workplace condition , long work hour. not having a rest day Such Week are important risk factrs of TB among rural adults out-migrating for woful the association that history of out-migrant for work in female with TB needs furber study in futurei.

关 键 词：肺结核 流行病学 外出打工 病例对照 

分 类 号：R521[医药卫生—内科学]