某高校1998～2006年新生乙型肝炎表面抗原阳性率状况  

THE STATUS OF POSITIVE RATE OF HEPATITIS B SURFACE ANTIGEN AMONG FRESHMEN IN A UNIVERSITY DURING 1998-2006

作　　者：梁亚荣[1] 何建丽[1] 陈芝茵[1] 

机构地区：[1]中国地质大学(武汉)校医院,武汉430074

出　　处：《现代预防医学》2007年第10期1954-1955,共2页Modern Preventive Medicine

摘　　要：[目的]了解近9年大学新生乙型肝炎(乙肝)的流行状况,为改进预防控制乙肝措施提供信息。[方法]新生入学体检时采取静脉血,采用酶联免疫吸附试验(ELISA)检测乙肝病毒表面抗原(HBsAg),丙氨酸氨基转移酶(ALT)采用日产CHEMIX-180型全自动生化分析仪及其配套试剂测定。[结果]1998～2006年HBsAg阳性率为6.34%～7.52%,各年间差异均无统计学意义(P﹥0.05),其中男生HBsAg阳性率7.12%～8.71%,女生HBsAg阳性率3.69%～5.23%,男生高于女生(P﹤0.01或P﹤0.05;HBsAg阳性伴有ALT异常率0.57%。[结论]大学新生入学体检进行HBsAg和ALT检测,并在入学后针对传染病的预防控制采取综合措施,是十分必要的。[Objective] To understand the epidemic status of Hepatitis B surface antigen mnong freshmen in a university during 1998-2006, and provide information for improving the preventive and control measures against Hepatitis B. [Methods] Venous blood were collected from matriculates. Surface antigen of hepatitis B virus （HBsAg） was detected using the enzymelinked immunosorbent assay （ELISA） method, Alanine Aminotransferase （ALT） was detected using CHEMIX-180 type automatic biochemistry analyzer and accompanying reagent made in Japan. [Results] During 1998-2006, the total positive rate of HBsAg ranged from 6.34% to 7.52%, without significant difference （P 〉 0.05） between adjacent years. Positive rate of HB- sag was 7.12%-8.71% for male students, 3.69%-5.23% for females, and the difference was significant （P 〈 0.01 or P 〈 0.05） . The rate of positive HBsAg accompanied by anomalous ALT was 0.57%. [Conclusions] It is highly necessary to include HBsAg and ALT detection during physical check-up for freshman students, and it is also very important to adopt comprehensive preventive and control measures in the subsequent years.

关 键 词：高校新生 乙型肝炎 表面抗原 

分 类 号：R512.62[医药卫生—内科学]