微波常压下快速合成L-噻唑烷-4-甲酸及其正丙酯的研究  

Study on Rapid Synthesis of L-thiazolidine-4-carboxylic Acid and L-Propyl thiazolidine-4-carboxylate under the Irradiation of Microwave and Conventional Pressure

作　　者：张昌军[1] 原方圆[1] 邵红兵[2] 王逸英[3] 王仁章[3] 马艳宁[3] 

机构地区：[1]泰山医学院化学与化学工程学院,山东泰安271000 [2]首都师范大学化学系,北京100037 [3]吉林师范大学应用化学研究所,吉林四平136000

出　　处：《化工时刊》2007年第5期51-52,共2页Chemical Industry Times

摘　　要：在微波常压条件下,以L-半胱酸为原料合成了L-噻唑烷-4-甲酸及其正丙酯,讨论了微波功率、催化剂用量和反应时间等因素对产率的影响。实验表明,微波技术可用于光学活性化合物的合成。并显示出微波合成的简便、安全、快速与产率高等特点。L- thiazolidine - 4 - carboxylic acid and L - Propyl thiazolidine - 4 - earboxylate were prepared by L - cysteine under the microwave irradiation at conventional pressure. And the feasibility of microwave technology in synthesizing optical active compounds was examined and the influences of microwave power and reaction time on the yield were discussed as well. The results show that microwave technology is a method with simplicity, safety, rapidity and high yield.

关 键 词：微波 合成 L-噻唑烷-4-甲酸 L-噻唑烷-4-甲酸正丙酯 

分 类 号：O626.25[理学—有机化学]