含羟基手臂双咪唑鎓氯盐的合成及其Pd络合物对Suzuki-Miyaura交叉偶联反应的催化活性  

Synthesis of N-Hydroxyalkyl-substituted Bisimidazolium Chloride Salt and the Catalytic Activity of Its Pd-complex for Suzuki-Miyaura Cross-coupling Reaction

作　　者：康泰然[1] 何龙[1] 陈联梅[1] 周丽梅[1] 王中华[1] 

机构地区：[1]西华师范大学化学化工学院,四川南充637002

出　　处：《合成化学》2007年第3期301-303,333,共4页Chinese Journal of Synthetic Chemistry

基　　金：西华师范大学研究生科研启动基金资助项目(05B021)

摘　　要：合成了一种新型含羟基手臂的双咪唑鎓氯盐(L.2HCl)。N2保护下L.2HCl与Pd(OAc)2原位制备N-杂环卡宾-Pd络合物。以DMF-H2O为溶剂,K2CO3为碱,该络合物催化溴代芳烃和芳基硼酸的Suzuki-Miyaura交叉偶联反应合成取代联苯,收率75%～99%。A novel N-hydroxyalkyl-substituted bisimidazolium chloride salt （L · 2HC1） was synthesized. A bis（N-heterocyclic-carbene）complex of Pd was prepared in situ under N2 from L · 2HCl and Pd（OAc） 2. The complex catalyzed Suzuki-Miyaura cross-coupling reaction of arylbromides with arylboronic acids in DMF -H2O using K2CO3 as a base to obtain substituted-biphenyl in yields of 75% - 99%.

关 键 词：双咪唑鎓氯盐 N-杂环卡宾 Suzuki-Miyaura交叉偶联反应 PD 络合物 合成 

分 类 号：O623.42[理学—有机化学] O625[理学—化学]