3-甲基-2-戊烯-4-炔醛的合成新方法  

An efficient synthesis of 3-methyl-2-penten-4-yn-1-hyde

作　　者：马荣华[1] 邹燕[2] 严春蓉[2] 吴凯群[2] 王玉良[2] 赵志刚[1] 

机构地区：[1]西南民族大学化学与环境保护工程学院,成都610041 [2]四川大学化学学院,成都610064

出　　处：《化学研究与应用》2007年第5期532-534,共3页Chemical Research and Application

摘　　要：A new method for synthesizing 3-methyl-2-penten-4-yn-1-hyde has been devoloped.Starting start with acetone,methyl formate,bromoethane etc,target molecule was given after adol reaction,addion reaction,grignard reaction and hydrolyze reaction.Effects of dosage of EtMgBr and method of synthesis were studied.The process provides an eco-friendly,high yielding synthetic methodology.The yield of producing 3-methyl-2-penten-4-yn-1-hyde was up to 45%.All products were determined by 1H NMR.A new method for synthesizing 3-methyl-2-penten-4-yn-1-hyde has been devoloped. Starting start with acetone, methyl formate, bromoethane etc, target molecule was given after adol reaction, addion reaction, grignard reaction and hydrolyze reaction. Effects of dosage of EtMgBr and method of synthesis were studied. The process provides an eco-friendly, high yielding synthetic methodology. The yield of producing 3-methyl-2-penten-4-yn-1-hyde was up to 45%. All products were determined by ^1H NMR.

关 键 词：3-甲基-2-戊烯-4-炔-1-醛 合成 乙炔化 

分 类 号：O623.54[理学—有机化学]