低强度激光抗氧化作用研究  

Research on Antioxidation of Low Intensity Laser

作　　者：颜红金[1] 王之光[2] 赵箭光[1] 崔淑仪 

机构地区：[1]广州医学院医学物理教研室,广东广州510182 [2]中山大学中山医学院激光医学研究室,广东广州510089

出　　处：《中国医学物理学杂志》2007年第3期187-188,162,共3页Chinese Journal of Medical Physics

基　　金：广州医学院基金项目(04-K-43)

摘　　要：目的:观察低强度激光对衰老模型小鼠的抗氧化系统的影响。方法:以D-半乳糖致小鼠亚急性衰老,低强度激光照射处理后,取小鼠血液,测量其T-SOD活性、GSH、MDA含量,观察其变化。结果:与模型组比较,大剂量组(B组)的T-SOD活性显著提高(P<0.01),GSH含量升高(P<0.05),MDA含量则显著降低(P<0.01),小剂量组(C组)各项指标与模型组比较无明显差异(P>0.05)。结论:一定剂量的低强度激光可影响D-半乳糖所致衰老模型小鼠抗氧化系统,增强抗氧化能力。Objective： To observe the effect on anti-oxidative system of the aging mice. Methods： Mice were aged caused by D-galactose. After these mice were irradiated by low intensity laser. The activity of SOD, the contents of GSH and MDA in blood of the mice were observed. Results： Low intensity laser irradiation can obviously promote the activity of SOD and the contents of GSH in blood, and also lower contents of MDA of aged model mice in B group. Conclusions： Some doses of low intensity laser irradiation can influence the antioxodative system and improve antioxidative ability of aging mice caused by D-galactose.

关 键 词：低强度激光 抗氧化 D-半乳糖 SOD 自由基 

分 类 号：R318.51[医药卫生—生物医学工程]