犬髋关节一过性滑膜炎关节内压的动物实验研究  

Animal experimental study on the intra-articular pressure change children with synoyitis of hip

作　　者：卢小虎 刘尚礼[2] 段贤斌 卢红 刘婕 

机构地区：[1]深圳市人民医院(暨南大学医学院附二院)骨科,深圳518020 [2]中山医科大学附属第二医院骨科,广州510010

出　　处：《重庆医科大学学报》2007年第6期643-644,656,共3页Journal of Chongqing Medical University

摘　　要：目的:在幼犬髋关节腔内注入2‰去甲肾上腺素,诱导髋关节一过性滑膜炎,动态观察髋关节内压的变化,探讨关节内压的变化对髋关节一过性滑膜炎的影响。方法:48只2～3月大小的幼犬,随机分为12组,每组4只,分别在髋关节内注入2‰的去甲肾上腺素,用99m锝-亚甲基二磷酸盐(99m TC-MDP)三相骨显像,在不同时间测定关节内压变化,同时观察股骨头局部循环血流、病理组织学变化、X-Ray照片检查。结果:去甲肾上腺素注入关节腔内后产生滑膜炎,关节内压增高,随着炎症消退而恢复正常,但最高不超过20mmHg,股骨头出现一过性缺血,未出现股骨头坏死。结论:髋关节一过性滑膜炎时,滑膜炎症导致关节内压增高,随着炎症消退关节内压恢复正常,关节内压变化影响股骨头供血情况,引起股骨头一过性缺血。Objective：To dynamically observe the change of intra-articular pressure of the hip by means of injecting 2‰ Noradrenaline（NA）into the hip joint cavity,to study the effects of intra-articular pressure change on transient synovitis of hip（TSH）. Methods：Fourty-eight dogs aged 2-3 months had been randomly divided into 12 groups,with four in each group All were injected 2‰NA into the hip joint an four assessments had been done.①The intra-articular pressure of hip was determined at different times. ②^99m TC-MDP triphasic imaging was used to observe the local blood supply of femoral head. ③Pathological changes were observed to understand the disease course.④X-ray was adopted to exmine the hip. Result：Noradrenaline induced transient synovitis of hip,and synovitis resulted in the increase of intra-articular pressure of hip which was over 20mmHg and lowered to be normal with the inflammation fading away.Transient blood insufficiency was observed in femoral head,but with no putrescence. Conclusion：In transient synovitis of hip,synovitis resulted in the change of intra-articular pressure hip,which changed to be normal as the inflammation faded away;and the intra-articular pressure change would influence the blood supply in femoral head,and could canse transient blood insufficiency.

关 键 词：髋关节 关节内压 滑膜炎 

分 类 号：R684.3[医药卫生—骨科学]