纤维支气管镜检查诊断胸内结节病的价值  

Analysis of the bronchospopic diagnosis of sarcoidosis

作　　者：徐益明 张新[2] 肖志英[2] 李菁[2] 贾友明[2] 白春学[2] 

机构地区：[1]江苏省无锡市锡山人民医院呼吸内科,江苏无锡214011 [2]复旦大学附属中山医院呼吸内科,上海200032

出　　处：《中国内镜杂志》2007年第5期528-530,共3页China Journal of Endoscopy

摘　　要：目的从不同角度探讨纤维支气管镜检查对胸内结节病诊断价值。方法回顾分析1999年10月～2005年6月行纤维支气管镜检查的55例结节病患者的临床资料。结果支气管镜下气道具有结节样病变组TBB阳性率为71.43%;而气道无结节样病变组TBB阳性率为21.74%(P=0.002)。支气管镜黏膜活检(TBB)联合经支气管肺活检(TBLB)阳性率为73.33%。灌洗液ACE浓度值大小与淋巴细胞百分比有明显相关性。结论纤维支气管镜检查对结节病诊断、判断病变活动度有较高的临床实用价值。[Objective ] To evaluate the role of fiberotic bronchopsy findings in the diagnosis of thoracic sarcoidosis. [Methods] A retrospective analysis was performed in 55 sarcoidosis patients from October of 1999 to June of 2005, [Results] The airway with endobronchial military lesions was found in 71.43% patients, while airway without endobronchial military lesions was 21.74% （P =0.002）. The diagnosis was comfirmed in 73.33% patients of combination transbronchial mucosa biopsy （TBB） and the transbronchial lung biopsy （TBLB） through fiberotic bronchos- py. The level of angiotensin-converting enzyme （ACE） is greatly related with the percent of lympphocytes in broncho-alveolar lavage fluid （BALF）. [Conclusions] The fiberotic bronchospy is clinically valuable for the diagnosis and the analysis activity of sarcoidosis.

关 键 词：结节病 诊断 支气管镜 肺泡灌洗 

分 类 号：R768.1[医药卫生—耳鼻咽喉科]