肉豆蔻酸-双层类脂膜修饰玻碳电极研究氯化血红素的电化学行为  

Electrochemical Behavior and Determination of Hemin at a Lipid-myristic Acid Modified Glassy Carbon Electrode

作　　者：金松子[1] 田文莉[2] 刘六战[2] 沈含熙[2] 

机构地区：[1]天津药物研究院,天津300193 [2]南开大学化学系,天津300071

出　　处：《分析测试学报》2007年第3期319-322,共4页Journal of Instrumental Analysis

基　　金：国家自然科学基金资助课题(29875011)

摘　　要：报道了氯化血红素在肉豆蔻酸-双层类脂膜修饰玻碳电极上的电化学行为。在0.1^-0.7 V(vs.Ag/AgCl)电位范围内,扫描速率为40 mV/s时,氯化血红素在-0.4 V处产生很灵敏的还原峰电流。于pH7.50.01 mol/L KH2PO4-Na2HPO4底液中,该氧化峰电流与氯化血红素浓度在7.32×10-9~1.57×10-6mol/L范围内呈良好线性关系。该电极可作为检测氯化血红素的新型的高灵敏度电化学生物传感器。This work reports the electrochemical behavior of hemin at a lipid-myristic acid modified glassy carbon electrode （GC）. In the potential range of ＋ 0. 1 - （ - 0. 7） V （vs. Ag,/AgCl）, an irreversible cathodic peak was observed at - 0. 4 V at the scan rate of 40 mV/s. In the medium of 0. 01 mol,/L KH2PO4 - Na2HPO4 （ pH 7.5 ）, the cathodic peak current shows linear relationship with the concentration of hemin in the range of 7.32 × 10^-9 - 1.57 × 10^-6 mol/L. It can be used for determining hemin with high sensitivity.

关 键 词：氯化血红素 双层类脂膜 肉豆蔻酸-双层类脂膜修饰电极 静电吸附作用 

分 类 号：O657.1[理学—分析化学]