不同剂量布托啡诺剖宫产术后硬膜外镇痛的研究  

A study on postoperative epidural analgesia after caesarean section with different dose of butorphanol

作　　者：张鹏[1] 金孝岠[1] 陈永权[1] 曹亚[1] 

机构地区：[1]皖南医学院附属弋矶山医院麻醉科,安徽芜湖241001

出　　处：《皖南医学院学报》2007年第2期144-146,共3页Journal of Wannan Medical College

摘　　要：目的:观察不同剂量布托啡诺剖宫产术后硬膜外镇痛效果。方法:60例(ASAI～Ⅱ级)剖宫产病人随机分成3组,对照组(BM组)、实验组1(B1组)、实验组2(B2组)。镇痛药物为:BM组(n=20)0.1125%布比卡因+0.004%吗啡;B1组(n=20)0.1125%布比卡因+0.004%布托啡诺;B2组0.1125%布比卡因+0.006%布托啡诺。采用负荷量+持续剂量给药模式,持续剂量背景流速3ml/h。结果:①VAS、BCS评分在术后8h,BM组低于B1组,BM组与B2组无明显差异。B1组与B2组各项评分无明显差异。②并发症:各组恶心呕吐、搔痒及呼吸抑制的发生率差异无显著性。结论:0.1125%布比卡因+0.006%布托啡诺剖宫产术后硬膜外镇痛效果确切,但不良反应的发生率与0.1125%布比卡因+0.004%吗啡组相比无明显改善。To observe the analgesic effects with different dose of butorphanol for postoperative epidural analgesia after caesarean section. Methods： 60 ASA Ⅰ～Ⅱ cases undergone caesarean section were randomly divided into control group（group BM, n = 20, mixture of 0.1125% bupivacaine and 0.004% morphine）. No. 1 experimental group（group BI, mixture of 0.1125 % bupivacaine and 0.004% butorphanol） and No. 2 （group B2, n = 20; mixture of 0. 1125% bupiva-caine and 0.006% butorphanol）. The three groups were carried out by loading-continuous administration with continuous doses of 3 ml/h by a pump. Results：①VAS and BCS in group BM were lower than that in group BI at 8 h during postoperative with no difference in 132. ②The in-cidence of nausea and pruritus in group BM was equivalent to group B1 or B2. Conclusion： Epidural administration of 0. 1125% bupivacaine and 0. 006% butorphanol will provide analgesia for post-caesarean section, but that produces obvious adverse effects.

关 键 词：布托啡诺 硬膜外 术后 镇痛 剖宫产 

分 类 号：R614.4[医药卫生—麻醉学] R971.1[医药卫生—外科学]