微量白蛋白尿与冠状动脉病变严重程度的关系  

The relationship between microalbuminuria and the serious degree of coronary heart disease

作　　者：贺涛[1] 陶建虹[1] 刘明江[1] 李钢[1] 

机构地区：[1]四川省人民医院心内二科,四川成都610072

出　　处：《现代医药卫生》2007年第11期1588-1589,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨微量白蛋白尿(MA)与冠心病冠状动脉病变严重程度的关系。方法:经冠状动脉造影确诊的冠心病患者(冠心病组)81例和非冠心病患者(对照组)54例,检测两组的尿白蛋白滤过率(UREA)及相关血脂、血糖等生化指标。结果:冠心病组尿白蛋白滤过率水平显著高于时照组(127.67±61.43)μg/min与(62.55±54.71)μg/min(P<0.01);相关分析显示尿白蛋白滤过率与冠脉狭窄指数呈正相关(P<0.05)。多元Logistic回归分析显示冠心病的发病与尿白蛋白滤过率有关。结论:微量白蛋白尿水平与冠心病冠状动脉病变程度密切相关,微量白蛋白尿是冠心病的独立危险因素之一。Objective：To explore the relationship between micrealbuminuria （MA） and the serious degree of coronary heart disease. Methods：One hundred thirty five patients were included in the study： normal control group（n=54） and cornoary heart disease（CHD） group （n=81）. All patients were diagnosised by comoary arteriongraphy. The lvevels of urinary albumin filtration rate （UREA）, blood-fat and blood glucose were analyzed respectively. Results：The levels of UREA in CHD group were significantly higher than those of normal control group（P〈0.01）. Correlation analysis showed that the levels of UREA are positively correlated with coronary artery stenosis exponent（P〈 0.05）. Muliple regression analysis （Logistic） showed the morbidity of CHD were correlated with UREA. Conclusion：The levels of UREA are closely correlated with the serious degree of coronary heart disease, MA is the independent risk factor in CHD.

关 键 词：微量白蛋白尿 冠状动脉疾病 危险因素 

分 类 号：R5[医药卫生—内科学]