疟疾12例临床及血液学特征  

Clinical and Hematological Features of 12 Cases of Malaria

作　　者：杨晓春[1] 刘杨[1] 

机构地区：[1]安徽省宿州市市立医院检验科,234000

出　　处：《实用全科医学》2007年第6期548-549,共2页Applied Journal Of General Practice

摘　　要：目的探讨疟疾患者临床特征、外周血象及骨髓象的变化。方法回顾性分析12例经骨髓涂片找到疟原虫证实为疟疾患者的临床资料。结果12例疟疾患者周期性发热12例,肝脾肿大6例,均无淋巴结肿大。外周血象:三系减少8例、二系减少4例。血涂片中易见单核细胞及异型淋巴细胞,均未见疟原虫。骨髓象:骨髓增生活跃6例,骨髓增生明显活跃6例,粒红比例<2∶1为8例,产生血小板型巨核细胞≤3/片11例。12例患者的骨髓涂片中均找到间日疟原虫。结论当外周血涂片检查疟原虫阴性时,了解疟疾的临床及血液学特征有助于疟疾患者的早期诊治。Objective To study the change of malarial patients＇clinical signs, hemogram and myelogram. Methods The clinical data of 12 cases of malarial patients, who were confirmed by finding malarial parasite in bone marrow, was analyzed retrospectively. Results Among the 12 cases, periodic fever appeared in 12 patients,hepatosplenomegaly in 6, no lymphadenectasis; three systems of peripheral hemogram decreased in 8, two systems of peripheral hemogram decreased in 4, monocyte and heterotypic lymphocyte were found in blood smear,no malarial parasite was found. Myelogram： myelosis activized in 6, myelosis activized obviously in 6. The proportion of granulocyte and erythrocyte 〈 2： 1 in 8, plateler type megakaryocyte ≤ 3/tablet in 11. Plasmodium vivax was found in 12 cases. Conclusions When the examination of malarial parasite in peripheral blood smear is negative, the clinical and hematological features of malaria are helpful for early diagnosis of malarial patients.

关 键 词：疟疾 血液学 误诊 

分 类 号：R531.3[医药卫生—内科学]