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机构地区:[1]郑州大学第二附属医院,河南省郑州市450014
出 处:《职业与健康》2007年第11期977-978,共2页Occupation and Health
摘 要:目的 探讨HBV母婴阻断方法及相关护理的阻断效果.方法 对43例妊娠合并乙型肝炎的待产妇从母孕28~30周开始,每隔4周肌内注射乙肝免疫球蛋白200 IU,连用3针,新生儿出生12 h内肌内注射乙肝免疫球蛋白200 IU,出生20d肌内注射乙肝疫苗第1针,第50天、6个月各肌内注射1支,并给予科学正确的护理方法.结果 2004年1月1日-2004年12月31日HBV携带产妇所生婴儿43例,7个月时复查婴儿乙肝生物标志物,5项全阴性者5例,抗-HBs+38例,乙肝疫苗接种成功率88%,HBV母婴垂直传播的阻断成功率100%.结论 此方法简便易行疗效确切.[ Objective] To explore a method to interrupt mother-infant transmission of HBV and a way of nursing care. [ Methods] Pregnant women were injected with anti-hepatitis B immunoglobulin of 200 international units intramuscularly every four weeks for 3 times from 28 to 30 gestation weeks ; newborn infants were injected with HBV immunoglobulin of 200 IU intramuscularly within 12 hours after birth, and hepatitis B vaccine on the 20th day, the 50th day and the sixth month after birth, meanwhile proper nursing was provided. [ Results] 43 infants were delivered by HBV-carrier parturients since Jan. 1st of to Dec. 31st of 2004; rechecking the five HBV markers in the 7th month, 5 infants were negative in all the 5 markers, 38 infants were found with positive anti-HBsAb; the successful rate of hepatitis B vaccination was 88% ; the vertical mother-infant transmission of HBV was totally interrupted. [ Conclusion] This method is easy and convenient with ensured therapeutic effect.
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