小叶榕叶水提物超频震动膜过滤工艺的研究  

Filtration study on aqueous extracts of Ficus microcarpa L.f. with vibratory shear-enhanced membrane filtration processing

作　　者：黄涛[1] 庞小雄[1] 周宏兵[1] 賴毅勤 李崇志 陈加林 

机构地区：[1]广东药学院药科学院,广东广州510006 [2]广州伟思过滤亚太技术有限公司,广东广州510631 [3]广州白云山制药厂,广东广州510515

出　　处：《广东药学院学报》2007年第2期116-118,128,共4页Academic Journal of Guangdong College of Pharmacy

基　　金：广东省科技厅资助项目(2005B33001005)

摘　　要：目的对超频震动膜过滤和传统水提醇沉工艺的分离、浓缩效果进行考察和比较。方法在小叶榕叶提取物的分离、纯化过程中,以相对除杂质率和总黄酮收率为指标,对截留孔径为A、B、C、D的超频震动膜进行试验考察,并与醇沉工艺效果进行比较。结果截留孔径为B的膜最适合小叶榕叶有效成分的分离,同时配合截留孔径的脱水膜,可使分离、浓缩快捷而连续地进行。结论在小叶榕叶的生产工艺中,超频震动膜过滤法可代替传统乙醇沉淀法及加热浓缩方法。Objective To compare the effect of routine ethanol sedimentation and vibratory shear-enhanced membrane filtration processing on separating and concentrating aqueous extractives of Ficus microcarpa L. f. Method Vibratory shear enhanced membrane filtration processing was used to separate and concentrate the active ingredients, total flavonoids from aqueous extractives of Ficus microcarpa L. f.. Membranes of four different pore sizes were equipped for the filtration system to investigate the filtration flux, stability, yield of active ingredients and foreign matter removal ability. Result Membrane B showed the best performance in separating active ingredients of Ficus microcarpace from crude extracts, while membrane D could concentrate active ingredients in membrane concentration mode. Vibratory shear enhanced membrane filtration processing made separation and concentration consecutively clone with remarkable superiority. Conclusion Vibratory shear enhanced membrane filtration is a good technology for replacing ethanol sedimentation and concentration in processing the extract of Ficus. microcarpa.

关 键 词：超频震动膜过滤 水提醇沉 小叶榕 

分 类 号：TQ461[化学工程—制药化工]