室缺肺高压手术的疗效观察  

Operation for Ventricular Septal Defect with Severe Pulmonary Hypertension

作　　者：杨再珍[1] 范书润[1] 冯光强[1] 邢志嵩[1] 王攀[1] 杨栋[1] 

机构地区：[1]郑州大学第五附属医院心脏外科

出　　处：《医药论坛杂志》2007年第6期4-6,共3页Journal of Medical Forum

摘　　要：目的　探讨手术治疗室缺合并重度肺高压的有效方法。方法　手术前静脉注射前列腺素E 1一周,术中应用顺单项活瓣修补室间隔缺损,术后再应用前列腺素E 1两周;同时,用彩超复查了解单项活瓣的分流作用。结果　术毕12例自动复跳,9例电除颤1－8次（5－20 J）后复跳。二次插管4例。围术期死亡两例,余19例术后彩超跟踪检查,其中7例可见到明显右向左通过活瓣的血流,时间持续3－17d后关闭;右束支传导阻滞5例。结论　顺单项活瓣补片同时前列腺素E 1静脉注射是一种治疗室缺并重度肺高压的有效方法。Objective To study the effective surgical method for the treatment of ventricular septal defects （ VSD ） with severe pulmonary hypertension （ PH ）. Methods ① Prostaglandin E1 （ PGE1 ） can be used one week before the operation and two weeks after the operation. ② Upward - unidirectional valve patch （UUVP） are used to repair the VSD. ③Shunt time of UUVP can be known by echocardiography. Results 2 cases were dead in the early postoperative period, the other 19 cases survived well except 5 cases which were remained with right bond - branch - block （RBBB）. Conclusion Postoperative right ventricular failure can be treated effectually by using UUVP and PG E1.

关 键 词：室间隔缺损 肺动脉高压 单向活瓣 前列腺素E1 

分 类 号：R654.2[医药卫生—外科学]