益气活血法对老年糖尿病患者左心室舒张功能影响的研究  

Effects of Supplementing Qi and Activating Blood Circulation Method on Left Ventricular Diastolic Function of Senile Diabetes

作　　者：衡先培[1] 杨柳清[1] 郭芳[1] 陈霞[1] 杨鸿[1] 吴丽凤[1] 

机构地区：[1]福建中医学院附属人民医院,福州350004

出　　处：《中华中医药杂志》2007年第5期313-315,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：福建省科技厅资助项目(No.K20068)

摘　　要：目的:研究益气活血法对100例老年糖尿病患者左室舒张功能的影响。方法:辨证分为4型:阴虚热盛型(YAEH)23例,气阴两虚型(DBQY)39例,阴阳两虚型(DBYY)14例,血瘀气滞型(QSBS)24例。用灯盏细辛注射液、生脉注射液分别静脉滴注,疗程2周。以彩色多普勒超声心动图于治疗前后分别测定左室舒张早期充盈峰值流速(VE)、左室舒张晚期充盈峰值流速(VA)、左室舒张早期充盈时间(ET),并计算VE/VA值。结果:益气活血法改善VE的顺序为DBYY>DBQY>QSBS>YAEH;降低VA为DBQY>DBYY>YAEH,QSBS略有增加;增加VE/VA比值为DBYY>DBQY,对YAEH影响较小,QSBS反降低;缩短ET为QSBS>DBYY>DBQY>YAEH。但DBQY、DBYY、QSBS三者间ET差异没有意义。结论:老年糖尿病左心室舒张功能异常无论辨证属DBQY、DBYY还是QSBS,都可用益气活血法治疗而获益;但属YAEH者不提倡用益气活血法。Objective： To prospectively investigate into the effects of supplementing QI and activating blood circulation method on left ventricular diastolic function of 100 cases of senile diabetics. Methods： The classification of syndrome were the following four types： 23 cases of extreme heat with yin asthenia（YAEH）, 39 cases of deficiency of both QI and YIN （DBQY）, 14 cases of deficiency of both yin and yang （DBYY） and 24 cases of QI - stagnation and blood stasis （QSBS）. Equal type was given intravenous drop infusion with fleabane injection added pulse-activating injection separately; time of therapy was two weeks. Meanwhile left ventricular diastolic early stage filling peak rate of flow（VE）, diastolic advanced stage filling peak rate of flow（VA）, time of diastolic early stage fiLling（ET） were determined separately with 2D color Doppler echocardiography before and after treatment. Meanwhile vale of VE/VA was calculated. Results： Group comparison displayed that the sequence of supplementing QI and activating blood circulation method improving VE was DBYY 〉 DBQY 〉 QSBS 〉 YAEH; the sequence of decreasing VA was DBQY 〉 DBYY 〉 YAEH, but VA slightly lifted in QSBS; the sequence of increasing the vales of VE/VA was DBYY 〉 DBQY, but vales of VE/VA has little changing in YAEH and has lowing in QSBS; he sequence of shortening ET was QSBS 〉 DBYY 〉 DBQY 〉 YAEH. But ET was no statistical significance discrepancy among DBQY, DBYY and QSBS. Conclusion： In clinic to aim directly at left ventricular diastolic dysfunction of senile diabetics, no matter syndrome differentiation belonging to DBQY, DBYY, QSBS, all can benefit after treatment with supplementing QI and activating blood circulation method; but syndrome differentiation belonging to YAEH advocates not to use supplementing QI and activating blood circulation method.

关 键 词：糖尿病 左室舒张功能 益气活血法 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]