低磁场术中磁共振导航的融合弥散张量成像功能研究  

The Integration of DTI and iMRI in Brain Surgery Involving Pyramidal Tracts

作　　者：姚成军[1,2] 毛颖[1,2] 张荣[1,2] 刘翌勋[3] 吴劲松[1,2] 庄冬晓[1,2] 周良辅[1,2] 

机构地区：[1]复旦大学附属华山医院神经外科,上海市神经外科临床医学中心 [2]复旦大学上海医学院神经外科学系,200032 [3]复旦大学数字医学研究中心

出　　处：《中国临床神经科学》2007年第3期241-247,共7页Chinese Journal of Clinical Neurosciences

摘　　要：目的:探讨低磁场术中磁共振成像(iMRI)导航手术利用弥散张量成像(DTI)的可能性和应用价值。方法:19例涉及锥体束的脑肿瘤患者,应用多影像融合技术将术前DTI与iMRI影像融合指导手术,术中利用非刚体配准计算法和手动点配准融合技术把修正的DTI逐层与更新的iMRI影像融合,并导航手术。术后随访肢体运动功能。结果:成功获得DTI变形预测结果,肿瘤全切除率63.2%,次全切除率15.8%,肢体运动较术前好转或维持术前症状者84.2%。结论:iMRI与DTI融合导航手术可实时提供病灶与邻近锥体束间三维可视化解剖信息,提高肿瘤切除率,降低术后致残率。To evaluate the likelihood and role of integration of diffusion tensor imaging （DTI） and intraoperative MRI （iMRI） of PoleStar N-20 in brain surgery involving pyramidal tracts.Methods： The preoperative DTI was merged into iMRI for neuronavigation by using manual point merge technique with non-rigid calculation in 19 patients with brain surgery involving pyramidal tracts. The relationship between the tumors and adjacent pyramidal tracts were segmented and reconstructed for three-dimensional visualization. The motor function of extremities was examined before and after operation. Results. The prediction and merge of DTI with iMRI were of success. The lesions were completely resected in 12 cases （63.2%）, subtotal in 15.8%. Postoperative neurological status was improved and stable in 84.2% cases. Conclusion. The integration of DTI and iMRI is feasible in neuronavigation surgery of brain surgery involving pyramidal tracts,

关 键 词：术中磁共振 弥散张量成像 神经导航 脑肿瘤 

分 类 号：R651.11[医药卫生—外科学] R816.1[医药卫生—临床医学]