Synthesis of 15-Demethyl Brefeldin A and Its 7-epi Isomer  

作　　者：沈鑫 杨永青 胡祺 黄嘉慧 高剑 伍贻康 

机构地区：[1]State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2007年第6期802-807,共6页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （Nos. 20025207, 20272071, 20372075, 20321202, 20672129, 20621062）, and the Chinese Academy of Sciences （Nos. NKGCX2-SW-209, KJCX2.YW.H08）.

摘　　要：Synthesis of 15-demethyl brefeldin A and its 7-epimer is detailed. X-ray crystallographic structure for 15-demethyl brefeldin A is also disclosed.Synthesis of 15-demethyl brefeldin A and its 7-epimer is detailed. X-ray crystallographic structure for 15-demethyl brefeldin A is also disclosed.

关 键 词：ANTIBIOTICS asymmetric synthesis ANALOGUE LACTONE 

分 类 号：TQ465.91[化学工程—制药化工] R979.14[医药卫生—药品]