Diels-Alder Reactions of N-Functionalized Acryloyl α-Pyrrolidone Derivatives Using FeCl3·6H2O as an Efficient Catalyst under Solvent-free Conditions  

作　　者：裴文 王永江 余长泉 

机构地区：[1]Chemical Engineering and Materials, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China

出　　处：《Chinese Journal of Chemistry》2007年第6期814-817,共4页中国化学（英文版）

摘　　要：Diels-Alder reactions of N-functionalized acryloyl α-pyrrolidone derivatives were investigated, which were catalyzed by FeCl3·6H2O as an efficient catalyst under solvent-free conditions at room temperature. The corresponding cycloadducts with functionalized-pyrrolidone were prepared in high yield with high stereoselectivity by a green chemistry procedure. N-Functionalized acryloyl pyrrolidone derivatives, a kind of pyrrolidone-functionalized chelating α,β-unsaturated ketone usable as a dienophile in Diels-Alder reaction, were synthesized by N-acylation procedure in ionic liquid as a novel synthetic method.Diels-Alder reactions of N-functionalized acryloyl α-pyrrolidone derivatives were investigated, which were catalyzed by FeCl3·6H2O as an efficient catalyst under solvent-free conditions at room temperature. The corresponding cycloadducts with functionalized-pyrrolidone were prepared in high yield with high stereoselectivity by a green chemistry procedure. N-Functionalized acryloyl pyrrolidone derivatives, a kind of pyrrolidone-functionalized chelating α,β-unsaturated ketone usable as a dienophile in Diels-Alder reaction, were synthesized by N-acylation procedure in ionic liquid as a novel synthetic method.

关 键 词：acryloylpyrrolidone derivative Diels-Alder reaction ferric chloride lewis acid SOLVENT-FREE 

分 类 号：O626.13[理学—有机化学] X383[理学—化学]