NH_3等离子体处理的PET表面接枝氨基酸的研究  

Grafting glutamic acid to a polyethylene terephthalate (PET) film treated with NH_3 plasma

作　　者：马晓星[1] 王秀芬[1] 张立群[2] 

机构地区：[1]北京化工大学化工资源国家重点实验室,北京100029 [2]北京化工大学教育部纳米材料制备及应用实验室,北京100029

出　　处：《北京化工大学学报（自然科学版）》2007年第3期290-292,325,共4页Journal of Beijing University of Chemical Technology(Natural Science Edition)

基　　金：化工资源国家重点实验室开放课题(2005-06-07);北京市自然科学基金重点项目(2061002)

摘　　要：用氨气等离子体处理聚对苯二甲酸乙二醇酯(PET)膜,在表面引入活性基团氨基,并通过戊二醛接枝谷氨酸。利用接触角、全反射傅里叶红外光谱(ATR-FTIR)、光电子能谱(XPS)和体外血液相容性实验(APTT)表征接枝改性后的膜的表面结构和性能,比较了只用氨气等离子体处理的膜和接枝谷氨酸后的膜的性能。结果表明,两种改性膜亲水性均提高,70 W放电功率下改性的膜血液相容性改善效果最好。与未处理的膜相比,用氨气等离子体处理的膜的APTT延长了5.9 s,接枝了谷氨酸的膜的APTT延长了3.2 s。Polyethylene terephthalate （PET） surfaces have been treated with NH3 plasma, and subsequently grafted with glutamic acid using glutaraldehyde as crosslinker. The extent of surface modification of the PET films was investigated by contact angle measurements, ATR-FTIR, XPS spectra and activated partial thromboplastin time （APTT） measurements. The properties of the films after treatment with NH3 alone were compared with those obtained after subsequent grafting with glutamic acid. It was found that the former are superior to the latter, and the blood compatibility was best when the power used was 70 W. The APTT times of the NH3- treated film and the grafted film were respectively 5.9 s and 3.2 s longer than that of the untreated film;

关 键 词：谷氨酸 PET膜 抗凝血性 等离子体 

分 类 号：R973[医药卫生—药品] TQ316.6[医药卫生—药学]