模拟失重下机体的整体调节(英文)  

Integrated Regulation in Response to Simulated Weightlessness

作　　者：杨光华[1] 崔伟[1] 孙亚志[1] 董颀[1] 沈羡云[1] 汪涛[1] 

机构地区：[1]航天医学工程研究所

出　　处：《航天医学与医学工程》1997年第1期1-5,共5页Space Medicine & Medical Engineering

摘　　要：大鼠悬吊１５ｄ和３０ｄ，同体同步采样进行多系统多指标观察模拟失重时的生理功能改变。结果表明：出现矿盐含量减少、比目鱼肌和腓肠肌Ｃａ２＋转运动能改变及红细胞变形性降低的同时，局部因子（骨细胞分泌的蛋白因子、肌浆网的Ｃａ２＋－ＡＴＰ酶）和全身性调节因子（免疫因子、生长激素）亦同步出现抑制现象，说明模拟失重时生理功能有着复杂的局部和整体调节过程。To investigate physiological effects of tail suspension,Ca 2+ concentration,immune factors,erythrocyte rheological properties,and growth hormone were determined in rats suspended for 15 and 30 d.The results showed that inhibitory changes of both local factors (proteins secreted by bone cell,Ca 2+ ATPase in sarcoplasmic reticium) and integrated regulative factors (immune factor,growth hormone) were observed simutaneously with the decrease of bone mineral content,calcium transportation in skeletal muscles as well as erythrocyte deformability.It suggests that both local and integrated regulative processes are functioning in response to the effects of weightlessness.

关 键 词：失重模拟 免疫因子 生长激素 红细胞流变性 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]