单采血小板前后献血者血清甲状旁腺素及电解质的变化  

Effect of an oral calcium load on serum electrolytes and PTH concentrations in healthy apheresis platelet donors

作　　者：洪缨[1] 郑碧华[1] 孟文[1] 刘桂然[1] 叶兰[1] 黄川丽[1] 吕桂珍[1] 林伟[1] 

机构地区：[1]成都市血液中心,四川成都610041

出　　处：《中国输血杂志》2007年第2期113-114,共2页Chinese Journal of Blood Transfusion

基　　金：四川省科技厅科研项目(编号:050174)

摘　　要：目的观察单采血小板前后献血者血清甲状旁腺素及电解质浓度的变化。方法选择单采血小板献血者45名,分为补钙组(n=11)和未补钙组(n=34),分别检测血小板采集前后血清甲状旁腺素(PTH)和钙、磷、钾、钠、镁离子浓度;献全血组(n=24)。结果单采后补钙组PTH浓度有统计学意义(t=2.472,P<0.05),未补钙组单采后磷浓度升高(t=3.191,P<0.05);单采血小板献血者采前血清磷、钙、钠的浓度低于对照组(t值分别为2.477,2.349和2.064,P<0.05),但仍在正常范围内。结论单采血小板会引起献血者血钙浓度短暂降低,但机体可自身迅速调节,不必常规补钙;单采血小板献血者采集前血清磷、钙、钠的浓度低于全血献血者。Objective To investigate the effect of an oral calcium load on serum electrolytes and PTH concentrations in healthy apheresis donors. Methods Forty-five apheresis donors were divided into two groups： calcium group （11 donors, taking oral calcium before apheresis） and no calcium group （34 donors）. Serum parathyroid hormone （PTH）, total calcium （Ca）, phosphorus （P）, potassium （K）, sodium （Na） and magnesium （Mg） were measured before and after the apheresis process. Twenty-four whole blood donors served as controls. Results After the apheresis process, PTH concentrations in calcium group and mean P in no calcium group increased significantly（ P 〈0.05）. Mean P, Ca and Na in apheresis donors before apheresis were lower than that in controls, but were still within the normal range. Conclusion Platelet apheresis may result in temporary citrate-induced hypocalcemia. Mean P, Ca and Na in apheresis donors before apheresis were lower than in controls.

关 键 词：单采血小板 甲状旁腺素 血清电解质 献血者 

分 类 号：R446.1[医药卫生—诊断学] R335.3[医药卫生—临床医学]