左氧氟沙星治疗ICU呼吸机相关性肺炎临床观察  

Levofloxacin for Patients with Ventilator Associated Pneumonia in ICU

作　　者：郭昌星[1] 林兆奋[1] 赵良[1] 杨兴易[1] 张强[1] 陈德昌[1] 单红卫[1] 管军[1] 李文放[1] 许永华[1] 

机构地区：[1]上海长征医院,上海200003

出　　处：《中华医院感染学杂志》2007年第5期597-598,共2页Chinese Journal of Nosocomiology

摘　　要：目的 评价左氧氟沙星注射液，治疗ICU呼吸机相关性肺炎的临床疗效及安全性。方法 共完成30例临床病例观察，左氧氟沙星注射液静脉滴注，1次／d，疗程7～10d。结果 痊愈率为53．33％，有效率为70．00％，细菌清除率为76．66％，不良反应发生率为6．67％。结论 左氧氟沙星注射液，治疗ICU呼吸机相关性肺炎安全、有效。OBJECTIVE To evaluate the efficacy and safety of levofloxacin on the patients with ventilator associated pneumonia in ICU. METHODS Thirty cases were observed and the dosage of drug was 500mg once a day for injection. The duration of the treatment was 7-10 days. RESULTS The total cure rate was 53. 33~, the total response was 70%, the bacterial clearance was 76.66%. CONCLUSIONS Levofloxacin is both effective and safe for patients with ventilator associated pneumonia in ICU.

关 键 词：左氧氟沙星 呼吸机相关性肺炎 重症监护病房 

分 类 号：R969.3[医药卫生—药理学]