睡眠呼吸暂停生活质量指数问卷在悬雍垂腭咽成形术近期评估中的应用  

Evaluation the short-term effects of uvulopalatopharyngoplasty on the sleep apnea quality of life index

作　　者：时蕾[1] 李延忠[1] 

机构地区：[1]山东大学齐鲁医院耳鼻咽喉科卫生部耳鼻喉科学重点实验室,山东济南250012

出　　处：《山东大学学报（医学版）》2007年第1期50-54,共5页Journal of Shandong University:Health Sciences

基　　金：山东省科技攻关计划项目资助课题(031050112)

摘　　要：目的:评价睡眠呼吸暂停生活质量指数(the sleep apnea quality of life index,SAQLI)问卷对悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apneahypopnea syndrome,OSAHS)的意义。方法:30例诊断为OSAHS并接受UPPP治疗的患者,术前行多导睡眠描记术(polysomnography,PSG)监测和SAQLI问卷调查,分析二者的相关性;手术4周后再进行SAQLI问卷调查,对2次结果进行比较。结果:术前OSAHS患者生活质量明显下降,主观问卷指标与呼吸暂停低通气指数(apnea hypopnea index,AHI)和最低血氧饱和度(lowest saturation,LSaO2)存在明显的相关性(P<0.01),SAQLI总分与AHI的相关系数为0.54,与LSaO2的相关系数为0.56。病情程度不同患者各个维度及总分得分在治疗前差异有统计学意义(P<0.01);术后患者SAQLI问卷各个维度及总得分均明显升高,差异有统计学意义(P<0.001),有86.7%的患者生活质量总体上得到改善。结论:UPPP手术能明显提高OSAHS患者近期内的生活质量。SAQLI问卷各个维度及总得分在不同病情程度患者治疗前后差异统计学意义,总得分与客观监测之间存在明显的相关关系,可用于中国成人OSAHS患者的生活质量评估,作为临床诊断和疗效观察的评价指标。Objective： To evaluate the significance of the sleep apnea quality of life index （SAQLI） for uvulopalatopharyngoplasty （UPPP） and quality of life in patients with obstruction sleep apnea hypopnea syndrome（OSAHS）. Methods： Thirty patients with OSAHS were diagnosed by PSG and treated by UPPP. SAQLI was surveyed before and after surgery. Results： Before operation, the score of SAQLI was greatly reduced and had significant statistically correlation with the apnea hypopnea index（AHI） （ r = - 0.54） and lowest saturation （ LSaO2 ） （ r = 0.56）. After operation, the total score of SAQLI including 4 domains increased significantly （P 〈 0.001 ）. Quality of life was improved in 86.7% cases in general. By SAQLI, we could discriminate among those with different qualities of life. Conclusion： The amelioration of quality of life in OSAHS patients is significant in the short term after UPPP. SAQLI can be a valuable measurement in clinical diagnosis and follow-up treatment.

关 键 词：睡眠呼吸暂停 阻塞性 悬雍垂腭咽成形术 睡眠呼吸暂停生活质量指数问卷 生活质量 

分 类 号：R766.7[医药卫生—耳鼻咽喉科]