婴儿巨细胞病毒感染相关胆汁淤积性肝炎  

Clinical Analysis of Infantile Cytomegalovirus Hepatitis with Cholestasis

作　　者：单庆文[1] 王琳琳[1] 云翔[1] 梁淡湄[1] 

机构地区：[1]广西医科大学第一附属医院儿科,南宁530027

出　　处：《实用儿科临床杂志》2007年第10期749-750,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的分析婴儿巨细胞病毒(CMV)感染相关胆汁淤积性肝炎患儿的临床特点。方法回顾性分析48例婴儿CMV胆汁淤积性肝炎的临床特点。同时观察23例婴儿CMV胆汁淤积性肝炎治疗后黄疸及肝功能指标变化。结果48例婴儿CMV胆汁淤积性肝炎患儿均有不同程度的黄疸、肝大和(或)脾大,肝功能异常。23例患儿经治疗后临床症状改善,血清总胆红素、结合胆红素及丙氨酸转氨酶较前下降较明显,但天冬氨酸转氨酶、碱性磷酸酶、γ-谷氨酸转移酶无明显下降。结论婴儿CMV胆汁淤积性肝炎的治疗应注意疗程个体化。Objective To investigate the clinical features of infantile cytomegalovirus （CMV） hepatitis with cholestasis. Methods The clinical features of infantile CMV hepatitis with cholestasis were retrospected in 48 cases and the liver function were detected before and after therapy in 23 cases. Results Forty - eight cases of infantile cytomegalovirus hepatitis with cholestasis had different degrees of jaundice, hepatosplenomegaly and abnormal liver functions. After therapy of 23 cases, the clinical symptoms and serum biochemical parameters such as bilirubin, alanine aminotransferase were improved , but serum parameters of aspartate aminotransferase , alkaline phospholipids and γ - glutamyltransferase had no improvement. Conclusion The theraphy of CMV hepatitis with cholestasis shall be individual.

关 键 词：巨细胞病毒 肝炎 婴儿 胆汁淤积 

分 类 号：R725.1[医药卫生—儿科]