不同分娩方式与早发型母乳性黄疸及胃肠激素水平的相关研究  

The relative investigation in different childbearing,early breast milk jaundice and gastrointestinal hormone

作　　者：贾丽霞[1] 祝佩芹[2] 王志红[3] 段海凤[4] 王红英[1] 潘丽霞[4] 

机构地区：[1]河北省邯郸市第一医院儿科,056002 [2]河北医科大学中医院妇产科 [3]河北省邯郸市第一医院麻醉科 [4]河北省邯郸市第一医院妇产科

出　　处：《中国妇幼保健》2007年第16期2207-2208,共2页Maternal and Child Health Care of China

基　　金：河北省2006年科学技术研究与发展指导计划项目〔0627611003〕

摘　　要：目的:探讨不同分娩方式与早发型母乳性黄疸发病率的关系及和胃动素(MOT)、胃泌素(GAS)水平的相关性。方法:由专人对该院产科出生正常的新生儿218例进行监测,其中剖宫产136例,自然分娩82例,将符合早发型母乳性黄疸诊断标准的50例对象进一步采集血液标本,通过放射免疫法测定MOT和GAS水平。结果:剖宫产组早发型母乳性黄疸的发病率为27.49%,高于正常分娩组发病率14.63%(P<0.05);剖宫产组MOT、GAS的水平分别为(206.84±32.10)ng/L和(94.54±16.42)ng/L明显低于正常分娩组(256.20±28.32)ng/L和(137.06±16.15)ng/L(P<0.001)。结论:剖宫产分娩的新生儿较自然分娩的新生儿更易发生早发型母乳性黄疸,且同时有胃肠激素MOT、GAS水平的降低。对剖宫产分娩的新生儿更应严密监测黄疸的发生,及早干预。Objective： To investigate the relationship of different childbearing, early breast milk jaundice and the blood level of motilin and gastrin. Methods：50 newborns with early breast milk jaundice were detected in 218 normal newborn （136 were delivered by caesarean and 82 were spontaneous delivered）. The blood level of motilin and gastrin in 50 were measured by radioimmunoassay to evaluate the difference between two groups. Results： The incidence of the early breast milk jaundice was 27.49% in caesarean deliver, but in sponta-neous delivered was 14. 63% （P〈0.05 ）.The level of MOT, GAS was 206. 84±32.10 and 94.54±16.42 （ng/L） in caesarean deliver, but the level was 256.20±28.32 and 137.06±16.15 （ng/L） （P〈0.001）in spontaneous deliver. Conclusion： The newborn delivered by caesarean is easier suffered by early breast milk jaundice than those spontaneously delivered, in the same time MOT and GAS are in a lower level. In case early breast milk jaundice happening, attention should be paid to jaundice in newborn delivered by caesarean.

关 键 词：分娩方式 母乳性黄疸 胃肠激素 

分 类 号：R714[医药卫生—妇产科学] R722.17[医药卫生—临床医学]