多裂骆驼蓬生物碱的提取及抗菌活性研究  

Studies on the extraction and bacteriocidal test of fungistatic agent extracted from Peganum multisectum Bobr by alcohol

作　　者：薛林贵[1] 赵国林[2] 张宝芹[1] 唐德平[1] 

机构地区：[1]兰州交通大学,甘肃兰州730070 [2]陇东学院

出　　处：《中兽医医药杂志》2007年第3期16-19,共4页Journal of Traditional Chinese Veterinary Medicine

摘　　要：采用乙醇回流提取法提取多裂骆驼蓬植物体中的生物碱类物质。通过杀菌活性试验和抗菌活性试验研究多裂骆驼蓬种子的乙醇提取物对供试的4种常见细菌的体外杀菌、抑菌活性。研究结果表明,随着提取液浓度的降低,杀菌、抑菌活性逐渐降低,但延长处理时间,其杀菌、抑菌活性升高,其中对金黄色葡萄球菌(Staphylococcus aureus)和普通变形杆菌(Proteus vulgaris)的杀菌活性最强,杀菌率可达90%以上。水溶性生物碱和脂溶性生物碱均具有抗菌活性,但水溶性生物碱的抗菌活性明显大于脂溶性生物碱。Desert plant-Peganum multisectum（Maxim） Bobr is a perennial herb of zygophyllaceae.The alkaloid was extracted from Peganum multisectum（Maxim） Bobr by the method of alcohol refluxing.It was found in the bioassay that the fungistatic agent of the alcoholic extracted from the seed of Peganum multisectum had remarkable bacteriocidal activities on four species of bacteria by the methods of bacteriocidal and microbiostatic test.Our results showed that the bacteriocidal activity decreased along with the decrease of agent concentration,but the bacteriocidal activity increased along with treatment time.Especially,bacteriocidal activity of agent was sighificantly increased over 90 percent while treated to Staphylococcus aureus and Proteus vulgarist.It was also found that the water -soluble and fat -soluble alkaloid extracts from P.umltisectum had remarkable anti-bacteria activity,but the former was ovbiously superior to the later.The results show that desert plant-Peganum multisectum Bobr is a potential farm chemical plant resource that need to open and apply.

关 键 词：骆驼蓬 生物碱 杀菌 抑菌活性 

分 类 号：S853.74[农业科学—临床兽医学]