天香丹治疗胸痹患者生活质量评价  

Effect of Tianxiangdan on quality of life in patients with angina pectoris

作　　者：洪军[1] 安冬青[1] 加力肯.吐尔逊 胡金霞[3] 

机构地区：[1]新疆医科大学附属中医医院干一科,新疆乌鲁木齐830000 [2]克州人民医院,阿图什845350 [3]新疆医科大学中医学院,新疆乌鲁木齐830000

出　　处：《新疆医科大学学报》2007年第5期440-442,共3页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区卫生厅青年科技人才专项基金资助(2001Y16)

摘　　要：目的:评价天香丹对胸痹(冠心病稳定型心绞痛)患者生活质量的影响。方法:64例冠心病稳定型心绞痛患者随机分为天香丹组(33例)、通心络胶囊组(31例),天香丹组在西医基础治疗上加服天香丹,每日服18g,分2次冲服;通心络胶囊组在西医基础治疗上加服通心络胶囊,每日服12粒,分3次口服。6个月为一疗程,观察2组患者治疗前、后心绞痛症状、中医综合证候指标与心电图的变化,并运用健康状况调查问卷(SF-36)和西雅图心绞痛量表(SAQ)评价患者治疗前、后生活质量的变化。结果:通心络胶囊、天香丹组改善心绞痛症状、心电图疗效及中医综合证候总有效率分别为64.52%、78.78%,64.52%、75.76%,83.87%、90.91%,2组差异均无统计学意义(P>0.05)。治疗后天香丹组心绞痛发作频率较通心络胶囊组明显减少(P<0.01)。天香丹在改善患者生理功能、总体健康、躯体活动受限程度方面明显优于通心络胶囊(P<0.05)。结论:天香丹能减少心绞痛的发作,改善胸痹患者生活质量,是治疗冠心病心绞痛的有效中成药。Objective： To evaluate the efficacy of Tianxiangdan for the improvement of quality of life in Xiongbi patients. Methods： Sixty-four stable angina patients were randomized into 2 groups, 33 cases as treatment group and 31 cases as controlled group. Patients took orally 9 g Tianxiangdan twice every day in the treatment group and 4 granules Tongxinluo Capsule three times everyday in the control group, and ask all patients undertook Western madicinal basic therapy. One cours of treatment which lasted for 6 months were undergone. During the courses of treatment, the following were observed to assess patients＇ quality of life, clinical symptoms of angina, EKG reading and symptoms of Chinese medicine. We survey SF-36 of the patients＇ health, and Seattle＇s angina SAQ before and after therapy indicator in order to evalute the quality of life in patients with angina pectoris. Results： After 6 months treatment, tow group improve the clinical symptoms of angina （64.52% in controlled group and 78.78% in treatment group）, curative effect of EKG （64.52% in controlled group and 75.76% in treatment group） and symptoms of Chinese medicine （83.87% in controlled group and 90.91% in treatment group ）. The discrepancy in two groups have no signifcance of statistics. After therapy, the frequency of angina in the treatment group were significantly lesser than that in control group （P 〈0.01） . In PF, GH and PL the Tianxiangdan group were significantly better than Tongcinluo group （P 〈0.05）. Conclusions： Tianxiangdan can decrease outbreak of angina and improve the quality of life in the Xiongbi patients, therefore it is an effective Chinese nostum for curing angina .

关 键 词：胸痹天香丹 生活质量 

分 类 号：R289[医药卫生—方剂学] R297.6[医药卫生—中药学]