超声激活血卟啉的机理初探  

The Study of Mechanism Ultrasound-activated Hematoporphyrin Derivatives

作　　者：刘渊声[1] 尚志远[2] 杨继庆[1] 胡健[3] 

机构地区：[1]第四军医大学物理教研室,西安710032 [2]陕西师范大学物理学院 [3]西安卫星测控中心

出　　处：《数理医药学杂志》2007年第3期385-387,共3页Journal of Mathematical Medicine

摘　　要：从超声空化产生的声致荧光出发,采用试管外包裹黑色塑料的方法将大量生理盐水的声致发光与其余能量形式分开,在相同条件下,使用集光球收集水槽中盐水的声致荧光,将荧光引出声场单独作用血卟啉。结果表明,水槽中盐水的空化热能、冲击波与试管中血卟啉溶液空化产生的高温、高压、冲击波等多种能量的合作用激活血卟啉。大量生理盐水的声致荧光太弱,不足以激活血卟啉。血卟啉被激活的同时,若有大量生理盐水声致荧光的存在,血卟啉的激活量将大大增加。An approach divides the sonoluminescence from the sound field by using test tube with black plastics and the isotropic light trap is applied to collect sonoluminescence in the trough which irradiates hematoporphyrin out of the sound field. The results of our work suggest that ultrasonically induced cavitation produces nonequilibrium high temperature, emits shock waves, together with the cavitation energy in hematoporphyrin solution activating hematoporphyrin. Only sonoluminescence energy has not enough energy to activate hematoporphyrin, but more hematoporphyrin will be activated when sonoluminescence is existing.

关 键 词：超声 血卟啉 声致荧光 

分 类 号：R312[医药卫生—基础医学] O426.1[理学—声学]