接枝丙烯酸亲水化改性聚砜超滤膜及其在多肽分离中的应用  

Hydrophilic surface modification of polysulfone hollow fiber membrane by acrylic acid treatment and its application to peptide separation

作　　者：董春华[1] 齐崴[1] 何志敏[1] 

机构地区：[1]天津大学化工学院化学工程研究所,天津300072

出　　处：《化工学报》2007年第6期1501-1506,共6页CIESC Journal

基　　金：国家自然科学基金项目(20306023);高校博士点基金项目(20050056061)。~~

摘　　要：Hydrophilic surface modification of polysulfone hollow fiber membrane was performed by acrylic acid treatment.Stannic chloride was selected as the proper catalyst, and phosphoric acid as the co-catalyst.The modification conditions, such as the ratio of the reagents (acrylic acid∶catalyst=1∶0.05), temperature (30℃) and reaction time (60 min), were optimized based on the contact angle measurements.The grafting of carboxyl group to the membrane surface was confirmed by IR spectrum and wettability analysis, and no degradation of the modified membrane skin or framework was observed with scanning electron microscopy.The experimental results of filtrating bovine serum albumin solutions indicated that the property of resisting protein adsorption on the membrane surface for the modified membrane was much better than that for unmodified membrane.In the process of separating casein hydrolysates, the advantages of modified membrane were also shown by comparing the permeate flux and molecular mass distribution with those of unmodified membrane.Hydrophilic surface modification of polysulfone hollow fiber membrane was performed by acrylic acid treatment. Stannic chloride was selected as the proper catalyst, and phosphoric acid as t.he cocatalyst. The modification conditions, such as the ratio of the reagents （acrylic acid ： catalyst= 1 ： 0.05）, temperature （30℃） and reaction time （60 min）, were optimized based on the contact angle measurements. The grafting of carboxyl group to the membrane surface was confirmed by IR spectrum and wettability analysis, and no degradation of the modified membrane skin or framework was observed with scanning electron microscopy. The experimental results of filtrating bovine serum albumin solutions indicated that the property of resisting protein adsorption on the membrane surface for the modified membrane was much better than that for unmodified membrane. In the process of separating casein hydrolysates, the advantages of modified membrane were also shown by comparing the permeate flux and molecular mass distribution with those of unmodified membrane.

关 键 词：丙烯酸 超滤 亲水聚砜膜 抗吸附 多肽分离 

分 类 号：TQ028.8[化学工程]