猪胸部枪弹伤后荧光眼底造影早期观察  

Early observation of fundus fluorescein angiography after gunshot wound in the chest of pigs

作　　者：韩非[1] 廖明松[2] 蒋炜[3] 胡健[4] 谌阳 何建春[5] 

机构地区：[1]第三军医大学研究生队,重庆400038 [2]成都军区总医院超声科,四川成都610083 [3]成都军区总医院眼科,四川成都610083 [4]成都军区总医院干部病房,四川成都610083 [5]成都军区总医院放射科,四川成都610083

出　　处：《西南国防医药》2007年第3期264-265,共2页Medical Journal of National Defending Forces in Southwest China

基　　金：成都军区"十五"面上项目(01A011)

摘　　要：目的:利用荧光眼底造影技术探讨猪胸部枪弹伤远达效应致眼部组织结构、视网膜血流伤后改变,了解胸部枪弹伤后眼组织的损伤情况。方法:采用高速弹射击10只猪(20只眼),建立胸部枪弹伤动物模型,对受试猪致伤前后不同时相点行眼底照相及荧光眼底造影,并作眼组织病理检查。结果:(1)眼底照相结果:伤后未见明显异常;(2)荧光眼底造影结果:伤后1 h耳-视网膜循环时间延长,较伤前有显著变化(P<0.05),伤后视网膜循环时间较伤前无显著改变;(3)病理结果:角膜上皮层肿胀、疏松,内皮层大量脱落,虹膜、睫状体、脉络膜、视网膜血管充血,血管内皮细胞部分脱落,视网膜神经纤维层水肿。结论:荧光眼底造影对胸部枪弹伤后,眼组织血流改变、视网膜功能的判断具有重要价值。Objective：To study the changes of eye tissue and retinal blood flow caused by thoracic gunshot wound remote effects by means of fundus fluorescein angingrsphy. Methods：The model of thoracic gunshot wound was established in 10 pigs. Their eyes（n=20） were collected. The changes of their eyes including pathological examination were observed with fundus fluorescein angingraphy before and after the various times. Results：（1 ） The eyeground photography showed that there was not obviously changes after the wound; （2） Fundus fluorescein angiogrsphy indicated that after wounded one hour, the ear - retinal circulation time delayed and was longer than that before of the pre - injury （P〈0. 05）, but the post - wound retinal cycle time did not change significantly. （3） Pathological findings included corneal epithelial swelling, endodermis abscission, congestive iris, ciliary body, choroid, abscission of retinal vascular endothelia/cells and retinal nerve fiber layer edema. Conclusion： Ftmdus fluorescein angiography is important to determine the changes of retinal blood flow and eye function after thoracic gunshot wound.

关 键 词：枪弹伤 荧光眼底造影 远达效应 

分 类 号：R826.5[医药卫生—临床医学]