持续硬膜外阻滞分娩镇痛的激素变化对宫缩的影响  

Effects of uterine contraction to hormonal change of birth process of continuous epidural block anesthesia of labor

作　　者：彭朗鸣[1] 尹春艳[2] 黄小鹏[2] 

机构地区：[1]南方医科大学中医药学院,510315 [2]广东省第二人民医院,510317

出　　处：《中国优生与遗传杂志》2007年第6期54-55,共2页Chinese Journal of Birth Health & Heredity

基　　金：广东省自然基金资助项目(040005053)

摘　　要：目的探讨持续硬膜外阻滞分娩镇痛的激素变化,认识分娩镇痛的规律。方法采用分娩镇痛和不采用任何镇痛技术阴道分娩的两组初产妇,比较血中前列腺素E1、前列腺素E2、皮质醇、内皮素的变化。结果在第三产程末,前列腺素E2、皮质醇及内皮素测定值下降显著,研究组与对照组之间有显著性差异。而前列腺素E1的含量虽下降,但研究组与对照组之间无显著性差异。结论在分娩镇痛后,促使子宫平滑肌收缩的激素含量下降时,会导致宫缩减弱。Objective： This paper diseusses the effeet of eontinuous epidural block to the birth process by studying the hormonal ehange during anesthesia of labor. Methods： We have ehosen two groups of spontaneous labor primipara, one with anesthesia during the labor as the experimental group and one without as the eontrol group. The ehange of the prostaglandin E1 , E2 , eortisol and endothelin between these two groups have been monitored. Results： At the end of the third stage of labor, the value of the prostaglandin E2, eortisol and endothelin deereased signifieantly for the experimental group while not for the eontrol group. There is some deerease of the prostaglandin E1 for the experimental group. However, the difference between these two groups was not obvious. Conelusion： The decrease of the hormonal indueed by the anesthesia of labor, whieh is to spur uterine smooth musele to eontraet, will weaken the uterine eontraetion.

关 键 词：膜外阻滞 分娩镇痛 宫缩 激素 

分 类 号：R714.3[医药卫生—妇产科学]