嘧菌环胺的合成与杀菌活性  

Synthesis of Cyprodinil and Its Fungicidal Activity

作　　者：柴宝山[1] 刘长令[1] 李志念[1] 

机构地区：[1]沈阳化工研究院,沈阳110021

出　　处：《农药》2007年第6期377-378,共2页Agrochemicals

基　　金：国家重点基础研究发展规划项目(2003CB114400);"十一五"国家科技支撑计划项目(2006BAE01A01-2)

摘　　要：以甲基环丙基酮和乙酸乙酯为原料,一步制得环丙酰基丙酮,再与苯基胍反应得到目标产物,其结构经核磁验证。室内生物活性测定结果表明该化合物具有广谱的杀菌活性,在100mg/L对白粉病、灰霉病、稻瘟病具有较好的防治效果,即使在25mg/L对灰霉病和稻瘟病仍有很好的防效。Cyprodinil was synthesized by reacting 1-phenylguanidine with 1-cyclopropylbutane-1,3-dione prepared from ethyl acetate and 1-cyclopropylethanone, and its structure was confirmed by; ^1H NMR. The biological test results in green house show that cyprodinil has good fungicidal activity against powdery mildew, gray mold and rice blast at 100 mg/L, and gives 80-100% control against gray mold and rice blast at 25 mg/L.

关 键 词：嘧菌环胺 合成 杀菌活性 

分 类 号：TQ455.4[化学工程—农药化工]