合成5,7-二硝基-8-羟基喹哪啶的一种新方法  

New method for synthesis of 5,7-dinitro-8-hydroxyquinaldine

作　　者：朱惠琴[1] 

机构地区：[1]淮阴师范学院化学系,江苏淮安223001

出　　处：《化学试剂》2007年第1期51-52,共2页Chemical Reagents

基　　金：江苏省高校自然科学研究项目(05KJD150041)

摘　　要：在乙腈、聚乙二醇存在下,8-羟基喹哪啶与硝酸铈铵反应生成标题化合物。8-羟基喹哪啶与硝酸铈铵的物质的量比为1∶1.4时,加热回流反应1.8 h,5,7-二硝基-8-羟基喹哪啶的产率可达78.3%。In the presence of acetonitrile and polyethylene glycol, 8-hydroxyquinaldine can react with cerium ammonium nitrate to form 5,7-dinitro-8-hydroxyquinatdine . A simple and mild method for the synthesis of 5,7-dinitro-8-hydroxyquinatdine was studied. The results showed that when the reaction mixture composed of 8- hydroxyquinaldine and cerium ammonium nitrate at a molar ratio of 1：1.4 was refluxed in the solvent for 1.8 h, the yield of 5,7- dinitro-8-hydroxyquinaldine was 78.3%.

关 键 词：8-羟基喹哪啶 硝酸铈铵 聚乙二醇 硝化反应 

分 类 号：O626.32[理学—有机化学]