中青年复性近视散光角膜形态改变及其相关因素  

Correlative factors for corneal morphous changes in young and middle aged patients with compound myopic astigmatism

作　　者：赵必诚[1] 王冬梅[1] 谭少健[1] 黄明汉[1] 

机构地区：[1]广西医科大学第一附属医院眼科,广西南宁530021

出　　处：《眼科新进展》2007年第6期448-449,共2页Recent Advances in Ophthalmology

摘　　要：目的探讨引起中青年复性近视散光角膜形态改变的相关因素。方法分别测量333例666眼18～46岁复性近视散光(-1.00DC以上)患者的角膜地形图、非接触眼压、角膜中央厚度(central corneal thickness,CCT),并进行散瞳检影验光、记录散光度数及轴位,将结果进行统计分析。结果角膜地形图的散光度与验光散光度呈正相关(r=0.68,P<0.01),其回归方程Y=0.145±0.678X(F=569.7,P<0.01);角膜地形图的散光轴与验光散光轴呈正相关(r=0.229,P<0.01);CCT与眼压呈正相关(r=0.422,P<0.01),其直线回归方程为Y=-3.479±0.037X(F=143.54,P<0.01),角膜CCT大约每增加37μm,眼压上升1mmHg(1kPa=7.5mmHg);CCT与屈光度无明显直线相关关系(r=0.003,P>0.1)。结论中青年复性近视散光68%由角膜散光决定,对患者作出诊断及处理之前,应进行全面的眼科检查。Objective To investigate the factors correlated to corneal morphous changes in young and middle aged patients with compound myopic astigmatism. Methods Coneal topography, non-contact tonometry（NCT） ,central corneal thickness （CCT） ,and retinophotoscopy were performed in 333 cases （666 eyes） with compound myopic astigmatism （ more than - 1.00DC）aged from 18 years old to45 years old. And the relationships among the parameters were analyzied statistically. Results A positive correlation between the astigmatism diopters examined by corneal photography and retinophotoscopy was detected （ r = 0.68,P 〈0.01 ） and the linear regression equation was Y=0.145 ± 0.678X（F = 569.7 ,P 〈 0.01 ）;A positive correlation was fotmd between the astigmatic axes examined by corneal potography and retinophotoscopy（ r = 0. 229, P 〈 0. 01 ） ; The correlation between NCT and CCT was significant（ r = 0. 422,P 〈 0.01 ） and the linear regression equation was Y = - 3. 479 ± 0. 037X （ F = 143.54,P 〈 0.01 ） that was to say an approximate increase ofl mmHg（1 kPa =7.5 mmHg） in NCT for an increase in CCT of 37 microns; There was no obvious linear correlation between the CCT and myopic diopter（ r = 0. 003, P 〉 0. 1 ）. Conclusion In young and middle age,68% astigmatism of eyes is determined by corneal astigmatism. A complete examination should be performed before making a diagnosis and deciding on a treatment.

关 键 词：复性近视散光 角膜地形图 角膜中央厚度 眼压 检影验光 

分 类 号：R770.43[医药卫生—眼科]