甲状腺功能亢进患者记忆功能的研究  

A study on memory function of patients with hyperthyroidism

作　　者：汪洪[1] 刘诗翔[1] 舒子正[2] 刘波[1] 

机构地区：[1]解放军昆明总医院神经内科,昆明650032 [2]解放军昆明总医院内分泌科,昆明650032

出　　处：《中国行为医学科学》2007年第6期507-508,共2页Chinese Journal of Behavioral Medical Science

摘　　要：目的了解甲状腺功能亢进患者的记忆功能。方法采用韦氏记忆量表对29例甲状腺功能亢进患者和20名健康对照者进行测试。结果对照组与患者组平均记忆商（MQ）之间比较[对照组（105．3±13．3）分，患者组（90．7±20．1）分]，差异有显著性（P〈0．01）。以记忆商≤85作为划界标准，有18例患者存在记忆障碍（18／29），达到62．1％，对照组仅有3人低于这一标准，2组间比较有显著性差异（ χ^2=7．06，P〈0．01）；患者组的甲状腺激素水平与记忆商之间呈负相关（r=-0．561和-0．573，P〈0．01）。结论甲状腺功能亢进患者存在不同程度的记忆障碍，记忆异常涉及记忆的多个环节，长时、短时及瞬时记忆均有受损，患者甲状腺激素水平或疾病程度与记忆成绩之间有一定联系。Objective To study memory function in patients with hyperthyroidism. Methods 29 patients and 20 normal controllers were tested with the revised Wechsler Memory Scale（WMS）. Results MQ of average scores in patient group （90.7 ± 20.1 ） was lower than that in the normal group（ 105.3 ± 13.3 ）, and the difference is significant （ P 〈 0.01 ）. Using MQ ≤ 85, a cut point, 18 of 29 patients had dysmnesia,3 of 20 controls was abnormal （ χ^2 = 7.06, P 〈 0.01 ）. In patient group, the level of thyroid-hormones （T3, T4） had significant negative correlation with MQ of WMS （ r = - 0. 561 and - 0.573, P 〈 0.01 ）. Conclusion Patients with hyperthyroidism show degrees of dysmnesia relating to the whole process of memory, and all of long-term, short-term memory and immediate memory are damaged to some degree. Between the achievements and the level of thyroid-hormones had some relation in patients with hyperthyroidism.

关 键 词：甲状腺功能亢进 病例对照研究 甲状腺激素 记忆 记忆障碍 

分 类 号：R686[医药卫生—骨科学]