震荡钝力性脑外伤实验性病理形态学研究  

Experiment study of pathological morphology on concussive blunt brain trauma

作　　者：盛延良[1] 李如波 李德祥 陈怀芳 张宪有[3] 张晓波[3] 刘东璞 孟宪群 张学仁 李宝德 

机构地区：[1]佳木斯医学院法医教研室 [2]中国医大 [3]佳木斯医学院病解教研室 [4]效区公安局 [5]鹤岗公安局

出　　处：《佳木斯医学院学报》1997年第1期3-5,共3页

摘　　要：本文以自制机械式流体液压冲击器,以平均382.1kPa 的压力,时间48.5-60.6ms 的液体冲击猫脑,造成了震荡性,钝力性脑外伤的病理模型。通过 HE,Nissle,Glees-Marsland 染色,显示出震荡性钝力所致原发弥漫性、局灶性脑损伤,以及继发外伤性脑损伤,同时表明震荡性钝力不但可形成脑震荡。In order to have a genaral view of morphological aspects of concussive blunt brain trauma[CBBT],24 cats were used by an arfificial mechanic fluid percussion impacter to exert impact uponcerebral top of the cats (average pressure 382.1kPa,time range 48.5-60.6ms)to establish an animal model.There was a normal control. Various morphological changes occurred following CBBT by checking up on macroscopic and microscopic after HE,Nissle,Glees-Marshland stains.The changes including both primary brain lesion[ie.coup brain contusion,contrecoup brain contusion.intermedial brain comtusion,central brain contusion,microuascular circulation disturbance and diffuse neurocyte injury with diffuse axonal injury(DAI)]and secondary brain injury [ie.secondary traumatic hamarhagic meningitis].DAI could be accompanied by neurocyte injury,cotrecoup cerebral contusion relatively common,especially central brain contusion,On the other hand,primary acute diffuse microuascular disturbance and diffuse neurocyte injury with DAI might be a morphological sign of serious brain concussion,which could be accompanied by cerebral contusion.

关 键 词：震荡钝力性 脑外伤 病理学 脑挫伤 病理 

分 类 号：R651.15[医药卫生—外科学]