糖尿病肾病中医证型与血浆TXB_2　6-keto-PGF_(Iα)的关系探讨  

On the relationship between plasma TXB 2 6-Keto-PGF Ⅰα and typology of TCM \ of diabetic renopathy

作　　者：唐红[1] 徐蓉娟[1] 胡健炜[1] 朱良争[1] 钟家宝[1] 

机构地区：[1]上海中医药大学附属龙华医院

出　　处：《辽宁中医杂志》1997年第1期3-4,共2页Liaoning Journal of Traditional Chinese Medicine

摘　　要：选择非胰岛素依赖型糖尿病（ＮＩＤＤＭ）肾病气虚血瘀型３１例、气阴两虚型３０例，分别测定血浆血栓素Ｂ２（ＴＸＢ２）和６－酮－前列腺素ＦＩα（６－ｋｅｔｏ－ＰＧＦＩα）。结果显示气虚血瘀型患者ＴＸＢ２明显升高，６－ｋｅｔｏ－ＰＧＦＩα明显降低，与气阴两虚组比有显著性差异（Ｐ＜０．０１～０．０５）。提示血浆ＴＸＢ２及ＰＧＦＩα的改变与ＮＩＤＤＭ肾病气虚血瘀证关系密切，并可作为ＮＩＤＤＭ肾病中医辨证分型的参考指标。NIDDM nephropathy patients were chosen in the study,of them 31 cases were Qi-deficency-Blood stasis type,30 cases were Both Qi and Yin deficency type,according to TCM diagnosis.The concentration of serum TXA 2 and 6-keto-PGF Iα in each patient were determined.It shows the concentration of serum TXA 2 in Qi deficency-Blood stasis group is significantly higher than that of controld and the concentration of serum 6-keto-PGF Iα is significantly lower than that of control.There are no difference of serum TXA 2 and 6-keto-PGF Iα in Both Qi and Yin,deficency group,comparing with the control.The result shows that the changing of the concertration of serum TXA 2 and PGF Iα is closely correlated with the type of Qi deficency-Blood stasis in NIDDM nephroathy patient.It can be used as the reference of TCM diagnosis.

关 键 词：肾病 气虚血瘀 TXB2 前列腺素 糖尿病 

分 类 号：R259.872[医药卫生—中西医结合] R277.52[医药卫生—中医内科学]