KF-Al_2O_3催化下二-γ-吡喃并[2,3-a;2',3'-f]萘衍生物的合成  

Synthesis of Di-γ-pyrano[2,3-a;2',3'-f]naphthalene Derivatives Catalyzed by KF/Al_2O_3

作　　者：周杰兴[1] 王香善[1] 曾兆森[1] 张梅梅[1] 史达清[1] 屠树江[1] 

机构地区：[1]徐州师范大学化学系

出　　处：《有机化学》2007年第6期786-789,共4页Chinese Journal of Organic Chemistry

基　　金：江苏省高校自然科学基金(No.04KJB150139)资助项目.

摘　　要：以芳醛、氰乙酸酯和1,5-萘二酚为原料,以乙醇为溶剂,在80℃以KF/Al2O3为催化剂合成了一系列的2,8-二氨基-4,10-二芳基-4H,10H-二-γ-吡喃并[2,3-a;2',3'-f]萘-3,9-二羧酸酯衍生物,该反应具有反应条件温和、产率良好、操作方便等优点.产物的结构通过IR,1HNMR和元素分析表征,并进一步通过X射线衍射分析确证4h的结构.A series of 2,8-diamino-4,10-diaryl-di-γ-pyrano[2,3-a;2＇,3＇-f]naphthalene-3,9-dicarboxylate derivatives have been synthesized by the reaction of aromatic aldehyde, cyanoacetate and 1,5-naphthalenediol in EtOH at 80 ℃ catalyzed by KF/Al2O3. The notable features of this procedure are mild reaction conditions, good yields and operational simplicity. The structures of the products were characterized by IR,^ 1H NMR spectra and elemental analysis, and 4h was further confirmed by X-ray diffraction analysis.

关 键 词：二-γ-吡喃并[2 3-a 2’ 3’-f]萘 KF-AL2O3 合成 

分 类 号：O643.32[理学—物理化学] O626[理学—化学]