富硒沼泽红假单胞菌对D-半乳糖致衰老小鼠抗氧化系统的影响  

Effects of Se-enriched Rhodopseudomonas palustris on Anti-oxidative System in Aging Mice Induced by D-galactose

作　　者：曩潇潇[1] 何瑶[1] 王晓炜[2] 闵涛玲[1] 杨启银[1] 周耀明[3] 

机构地区：[1]南京师范大学生命科学学院微生物工程重点实验室,江苏南京210097 [2]南京师范大学金陵女子学院,江苏南京210097 [3]南京师范大学化学与环境科学学院,江苏南京210097

出　　处：《安徽农业科学》2007年第16期4850-4852,共3页Journal of Anhui Agricultural Sciences

基　　金：江苏省科学技术厅(BG2005326)

摘　　要：用沼泽红假单胞菌和富硒沼泽红假单胞菌灌喂衰老模型小鼠(用D-半乳糖制备),60 d后检测小鼠血液、血清、肝组织中超氧化物歧化酶(SOD)活力,谷胱甘肽过氧化物酶(GSH-PX)活力和丙二醛(MDA)含量及T-AOC能力。结果表明:富硒沼泽红假单胞菌可显著提高D-半乳糖衰老模型小鼠血液、血清、肝组织SOD活力、GPX-PX活力,使T-AOC能力明显增高,使衰老小鼠体内MDA含量明显下降。富硒沼泽红假单胞菌可显著提高D-半乳糖衰老模型小鼠的抗氧化能力。In the paper,the mice were treated through injecting Rhodopseudomonas palustris and se-enriched Rhodopseudomonas palustris into their abdominal cavity.The contents of Superoxide dismutase（SOD）,malondialddede（MDA）,Glutathione Peroxidase（GSH-PX） and T-AOC capacity in the blood,serum and liver tissue were tested after 60 days.The results showed that in se-enriched Rhodopseudomonas palustris treating groups,SOD,GSH-PX and T-AOC were increased and MDA was decreased.This suggested that se-enriched Rhodopseudomona palustris could strikingly incrase antioxidation in aging mice induced by D-galactose.

关 键 词：硒 沼泽红假单胞菌 SOD GSH—PX T-AOC MDA 

分 类 号：Q939.9[生物学—微生物学]