清咽喷雾剂的抗炎和抑菌作用研究  

Study on the Anti-inflammatory and Bacteriostatic Effects of Qingyan Spray

作　　者：陈燕 滕宝霞[2] 

机构地区：[1]兰州石化总医院药剂科,甘肃兰州730060 [2]甘肃省药品检验所,甘肃兰州730000

出　　处：《药学进展》2007年第6期274-276,共3页Progress in Pharmaceutical Sciences

基　　金：2006年兰州石油化工总公司科技资助项目LZSH-JSKF-2006-10;甘肃省科技攻关项目(2GSO42-A43-O14-11)

摘　　要：目的:观察清咽喷雾剂的抗炎和体内、体外抑菌作用。方法:通过小鼠耳肿胀试验、小鼠毛细血管通透性试验、大鼠肉芽肿试验,观察清咽喷雾剂对急性炎症、慢性炎症的作用;通过体内、体外抑菌试验,考察清咽喷雾剂的抑菌作用。结果:清咽喷雾剂中、高剂量组均能抑制小鼠毛细血管通透性,抑制小鼠琼脂肉芽肿的增长,清咽喷雾剂体内、体外对致病菌有抑菌作用。结论:清咽喷雾剂具有抗炎和抑制致病菌的作用。Objective： To study the anti-inflammatory effect and the bacteriostatic effect of Qingyan spray in vivo and in vitro. Methods： Acute and chronic anti-inflammatory effect of Qingyan spray was observed through the ear edema, capillary permeability in mice, granuloma in rats. Bacteriostatic effect of Qingyan spray was investigated using the bacteriostatic test in vivo andin vitro. Results： Qingyan spray in middle and high dosage has suppressive function on capillary permeability and granuloma induced by agar in mice. Con. elusion： Oingyan spray has anti-inflammation and bactefiostasis effects.

关 键 词：清咽喷雾剂 耳肿胀 毛细血管通透性 肉芽肿 抑菌作用 

分 类 号：R285.5[医药卫生—中药学]