正交试验优选郁乐舒颗粒中柴胡的提取工艺  

Optimization of the Extraction Process of Saikosaponin from Yuleshu Granule by Orthogonal Experiment

作　　者：方道硕[1] 

机构地区：[1]成都铁路中心医院药剂科,成都市610081

出　　处：《中国药房》2007年第18期1383-1384,共2页China Pharmacy

摘　　要：目的:优选郁乐舒颗粒中柴胡的提取工艺。方法:采用正交试验法,以柴胡皂苷a、干膏收率等多指标综合评分筛选柴胡最佳提取工艺。结果:最佳提取工艺为加7倍量的60%乙醇,回流提取2次,每次1h。结论:优选的提取工艺设计合理、结果稳定、提取率高。OBJECTIVE： To optimize the extraction process of Radix Bupleuri in Yuleshu granule, METHODS： The extraction process of Radix Bupleuri was optimized by orthogonal experiment with the extract yields of Saikosaponin-a and dry extract taken as observing indexes. RESULTS： The optimal extraction process was as follows： 7 times of 60% alcohol was added and reflux extraction was performed twice （one hour in each time）. CONCLUSION： The optimized extraction process is reasonable in design, stable in results and high in extraction yield.

关 键 词：柴胡 柴胡皂苷A 正交试验 提取工艺 

分 类 号：R284.2[医药卫生—中药学] R283.627[医药卫生—中医学]