超体质量、肥胖及黑棘皮病与空腹指血血糖相关性调查  

The Survey of Relation between Overweight,Obesity,Acanthosis Nigricans and Fasting Capillary Whole Blood Glucose

作　　者：梁学军[1] 侯冬青[2] 巩纯秀[1] 曹冰燕[1] 颜纯[1] 

机构地区：[1]首都医科大学附属北京儿童医院 [2]首都儿科研究所

出　　处：《首都医科大学学报》2007年第3期292-295,共4页Journal of Capital Medical University

基　　金：首都医学发展基金(2002-2005);北京市科委重大项目基金(H030930030430;H030930030031)资助项目~~

摘　　要：目的通过对超体质量、肥胖及黑棘皮病的儿童青少年空腹末梢指血血糖的测定,进一步探讨超体质量、肥胖及黑棘皮病对儿童青少年血糖的影响。方法对19 112例北京市在读6-18岁中小学生进行临床查体,包括皮肤黑棘皮病及身高、体质量等,测定空腹末梢指血血糖。结果超体质量、肥胖和黑棘皮病儿童青少年检出率分别为21.38%、9.7%和2.43%。在空腹末梢指血血糖≥5.6 mmol/L和≥6.1 mmol/L 2组,超体质量、肥胖儿童青少年阳性率分别显著高于空腹末梢指血血糖〈5.6mmol/L和〈6.1 mmol/L 2组,本调查还发现在空腹末梢指血血糖≥5.6 mmol/L组黑棘皮病儿童青少年阳性率显著高于空腹末梢指血血糖〈5.6 mmol/L组。5.6 mmol/L和6.1 mmol/L两界值比较,后者并没有显示出优势。结论6-18岁超体质量、肥胖及黑棘皮病学龄儿童青少年出现空腹末梢指血血糖≥5.6 mmol/L几率显著增高。超体质量、肥胖及黑棘皮病学龄儿童青少年应作为糖尿病的高危人群进行早期筛查,建议空腹末梢指血血糖分界值为5.6 mmol/L。Objective The strong relation between type 2 diabetes mellitus and overweight, obesity, obesity with acanthosis nigricans is widely concerned. In this study we determined the fasting capillary whole blood glucose （ FCBG ） of school children and adolescence and investigate the relation between overweight, obesity, acanthosis nigricans and FCBG further to make sure the normal level of FCBG for children and adolescence. Methods A total of 19 112 school children and adolescence from six regions of Beijing and aged 6 to 18 years were measured for height, weight, acanthosis nigricans and the FCBG, Their mean age was （12. 564 ±3. 280） years, They were divided into normal weight group, overweight group and obesity group according to body mass index（BMI）-overweight and obesity screening standard of Chinese school children and adolescence. Results The overall prevalence of overweight, obesity and acanthosis nigricans were 21.38%, 9.7% and 2.43% respectively. In the group with FCBG≥5.6 mmol/L, the positive rate of overweight was 29.85%, significantly higher than that with FCBG 〈 5.6 mmol/L 21.38%, （Х^2 Value = 20.50, P 〈 0.01 ）. In the group FCBG ≥6.1 mmol/L, the positive rate of overweight was 35.92%, significantly higher than that with FCBG 〈 6. 1 mmol/L, 21.31% （Х^2 Value = 13.02, P 〈0.01 ）. In the group with FCBG≥5.6 mmol/L, the positive rate of obesity was 15.99%, significantly higher than that with FCBG 〈 5.6 mmol/L 9.54% （Х^2 Value = 21.77, P 〈 0.01 ）. In the group with FCBG 1〉 6.1 mmol/L, the positive rate of obesity was 20.39%, significantly higher than that with FCBG 〈 6.1 mmol/L, 9.64% （Х^2 Value = 13.52, P 〈 0.01 ）. In the group of FCBG ≥ 5.6 mmol/L, the positive rate of obesity children and adolescence with acanthosis nigricans was 5.76%, significantly higher than that of FCBG 〈 5.6 mmol/L2.43%, （Х^2 Value = 22.5, P 〈 0.01 ）. The critical point 6. lmmol/L did not show any advantage when compared with the point 5.6 mmol/L. Conclusion 6 - 18 year

关 键 词：超体质量 肥胖 黑棘皮病 空腹指血血糖 儿童 

分 类 号：R587.1[医药卫生—内分泌]