青蒿素的制备、用途和展望  

Preparation application and prospect of artemisinin

作　　者：阮栋梁[1] 王丰玲[2] 张英锋[2] 郑向军[3] 

机构地区：[1]香港大学化学系 [2]河北省秦皇岛市第一中学,河北秦皇岛066000 [3]北京师范大学化学系,北京100875

出　　处：《渤海大学学报（自然科学版）》2007年第2期108-112,共5页Journal of Bohai University:Natural Science Edition

基　　金：国家自然科学基金资助项目(No:20501003)

摘　　要：青蒿素是含有过氧桥的新型倍半萜内酯,其衍生物有青蒿琥酯、蒿甲醚和二氢青蒿素等。青蒿素是有效的疟疾治疗药物,此外它还具有抗肿瘤、抗寄生虫、影响免疫等药理作用。对青蒿素及其衍生物进行了综述。Artemisinin with an endoperoxide function was derived from artemisia by Chinese research workers in 1972. Its derivatives include artesunate, artemether, dihydroartemisinin etc. Artemisinin,which is the most effective antimalarial drug,has other pharmacological activity such as antitumor ,antischistosome,affecting immunity etc. This article summarizes the research progress of artemisinin and its derivatives to provide references for the expoitation and utilization.

关 键 词：菁蒿素 抗疟痰 药理作用 

分 类 号：R282.76[医药卫生—中药学]