正常人血小板介电谱的实验研究  

Experimental Research for Dielectric Spectroscopy of Normal Human Platelets

作　　者：崔湘屏[1] 马青[1] 丁方[2] 

机构地区：[1]宁波大学医学院生理学与药理学研究所 [2]宁波市医疗中心李惠利医院脑外科,宁波315041

出　　处：《生物医学工程学杂志》2007年第3期682-684,共3页Journal of Biomedical Engineering

基　　金：浙江省卫生厅科研项目资助(20044B176);宁波市科技项目资助(2004002;2006C100116);宁波大学王宽诚幸福基金和人才基金资助

摘　　要：在100KHz～110MHz范围内,测量人血小板的介电谱,分析了人血小板对交流电场的介电响应的数据特征。利用频域阻抗技术首次测量了正常人血小板交流阻抗,绘制血小板的介电常数和电导率与电场频率的关系曲线。建立了人血小板的介电谱和Cole-Cole图,明确了人血小板的介电频响的数据特征。在射频电场中,人血小板的介电常数和电导率具有频率依赖性,血小板介电谱具有两个特征频率:第一特征频率fC1为6.66MHz,第二特征频率fC2为9.81MHz。The dielectric spectroscopy of human platelets was measured within the frequency range of 100 KHz-100 MHz, and the dielectric numerical characters of human platelets in response to AC electric field were analyzed. We measured the AC impedance of normal human platelets with the impedance technique in the frequency domain for the first time. The experimental data were used to draw a relationship curve between the frequency of electric field and permittivity or conductivity, and then the dielectric spectrum and the Cole-Cole plos of human platelets were established and then, the characteristics of dielectric response of human platelets were decided, which demonstrated the dependence of permittivity and conductivity of human platelets upon frequency, and showed two characteristic frequencies of the dielectric spectroscopy of human platelets ： the first characteristic frequency fc1=6.66 MHz; the second characteristic frequency fc2= 9.81 MHz.

关 键 词：人血小板 介电谱 介电常数 电导率 Cole-Cole图 

分 类 号：R35[医药卫生—基础医学]