新型脱氧胆酸钳形阴离子受体的设计合成及其对阴离子的识别性能研究  

Design and synthesis of novel tweezer anion receptors based on deoxycholic acid and molecular recognition properties for anions

作　　者：刘兴利[1] 赵志刚[1] 

机构地区：[1]西南民族大学化学与环境保护工程学院,成都610041

出　　处：《化学研究与应用》2007年第6期670-674,共5页Chemical Research and Application

基　　金：四川省应用基础研究项目(04JY029-003-08)

摘　　要：A novel type of molecular tweezer receptors based on deoxycholic acid has been designed and synthesized.Their structures were characterized by 1H NMR,IR,MS spectra and elemental analysis.Their binding properties for anions were examined by UV-vis spectra titration.The results show that the molecular tweezers 5a and 5b have good recognition properties for the anions examined and the supramolecular complexes formed between the hosts and guests consist of 1∶1 host and guest molecules.The main driving forces are the multiple hydrogen bonding interactions between host and guest molecules.The selective sequence is F->Cl->Br->I->AcO->H2PO4-.A novel type of molecular tweezer receptors based on deoxyeholie acid has been designed and synthesized. Their structures were characterized by ^1H NMR, IR, MS spectra and elemental analysis. Their binding properties for anions were examined by UV-vis spectra titration. The results show that the molecular tweezers 5a and 5b have good recognition properties for the anions examined and the supramolecular complexes formed between the hosts and guests consist of 1：1 host and guest molecules. The main driving forces are the multiple hydrogen bending interactions between host and guest molecules. The selective sequence is F^- 〉 Cl^- 〉 Br^- 〉 I^- 〉 AeO ^-〉 H2PO4^-.

关 键 词：脱氧胆酸 分子钳 阴离子 分子识别 合成 

分 类 号：O641.3[理学—物理化学]