处理后活动精子总数及授精次数对宫腔人工授精妊娠结局的影响  

Effects of processed total motile spermatozoa count and times of insemination on the intrauterine insemination pregnancy outcome

作　　者：郭江华[1] 黎平[1] 邓爱民[1] 李冬梅[1] 

机构地区：[1]广东省江门市中心医院生殖中心,江门529000

出　　处：《华北煤炭医学院学报》2007年第4期465-467,共3页Journal of North China Coal Medical College

摘　　要：①目的 探讨同一周期精液处理后活动精子总数（PTMS）及授精次数对官腔内人工授精（IUI）妊娠结局的影响.②方法 回顾性分析了234个IUI周期的临床资料.将不同的PTMS区间分成4组,比较PTMS对IUI妊娠结局的影响;同时比较同一周期中单次和双次IUI对妊娠结局的影响.③结果 234个IUI治疗周期中各组PTMS分别为≥40×10^6、（40～20）×10^6、（20～10）×10^6、≤10×10^6.所获得的临床周期妊娠率分别为17.14%、16.13%、17.50%、7.03%,其中第4组与其余3组比较有显著性差异（P＜0.05）;136个单次IUI周期和98个双次IUI周期各获得11.11%和12.24%的周期临床妊娠率,两组比较显著性差异（P＞0.05）.④结论 PTMS≤10×10 ^6时周期临床妊娠率明显下降;同一周期授精次数对IUI妊娠结局无明显影响.Objective To explore the effects of processed total motile spermatozoa count （PTMS） and times of insemination per cycle on the clinical pregnancy outcome after intrauterine insemination （IUI）. Methods The clinical data of 234 cycles was analyzed by a retrospective survey. The space of PTMS was separated into four groups and effects of PTMS and times of insemination on IUI pregnancy outcome were compared. Results The PTMS of each groups is ≥40 ×10^6 ,（40 -20） ×10^6 ,（20 - 10） ×10^6 and≤10 ×10^6 ,which corresponding clinical pregnant rate is 17.14% ,16.13% ,17.50% and 7.03% in 234 treated cycles. There was significant difference between group 4 other groups （P 〈 0.05 ）. There is no difference in the clinical pregnant rate between 136 cycles with single time IUI and 98 cycles with double（ 11.11% vs 12.24% ,P 〉 0.05 ）. Conclusion Clinical pregnant rate declined distinctively when PTMS ≤ 10 ×10^6, but the times of IUI had no impact on the pregnancy outcome.

关 键 词：官腔内人工授精 妊娠 活动精子总数 

分 类 号：R714[医药卫生—妇产科学]