48例多器官功能障碍综合征临床分析  

Clinical Analysis of 48 Patients with MODS

作　　者：刘八一[1] 李平[1] 郭应军[1] 侯杰[1] 

机构地区：[1]广州中医药大学附属中山医院综合ICU,中山528400

出　　处：《白求恩军医学院学报》2007年第3期146-147,共2页Journal of Bethune Military Medical College

摘　　要：目的探讨多器官功能障碍综合征(MODS)的临床特征。方法收集ICU收治的48例MODS患者的临床资料,通过列表收集资料进行总结和统计分析。结果年龄、肝和肾功能衰竭等与患者的死亡关系显著;2个器官衰竭者患者死亡率为12.4%,3个器官为57.1%,4个或以上器官衰竭者病死者为100%;MODS诱因以感染为最多,达50%,其中肺部感染占37.5%;首发衰竭器官的发生以肺最常见,占29.2%。结论肾功能和肝功能衰竭是造成MODS患者死亡率高的两个危险因素;控制感染可强化MODS治疗;早期支持首发器官可预防MODS。Objective To analyze the dinieal characteristics of multiple organ dysfunction syndrome（MODS）. Methods The data from 48 patients with MODS in ICU were summarized and analyzed re-rely. Results The high risk factors such as age, renal and hepatic failure were significantly correlated with mortality of patients with MODS. Mortalities of patients with two,three,four and more failed organs were 12.4%, 57.1% and 100% respectively.Infection was the main revulsive factor of MODS which pulmonary infection was the first（37.5% ）. Pulmonary failure was most common in initial failure organ. Conclusion Renal and hepatic failure were the high risk factors in mortality of MODS. Controlling infection can strengthen therapy on MODS. Actively treating primary disease should be beneficial to preventing MODS.

关 键 词：多器官功能障碍综合征 临床分析 

分 类 号：R422.8[医药卫生—临床医学]