妊娠中期孕妇血清C反应蛋白水平预测早产的临床研究  

Clinical Study on Serum C-reactive Protein Level in Midtrimester Pregnancy in Predicting Premature Delivery

作　　者：罗雪梅[1] 周昌菊[2] 程秋蓉[3] 杜建林[1] 

机构地区：[1]吉首大学医学院,湖南吉首416000 [2]中南大学湘雅三医院妇产科 [3]吉首大学第一附属医院妇产科

出　　处：《实用预防医学》2007年第3期804-805,共2页Practical Preventive Medicine

基　　金：湖南省教育厅资助课题(NO.05C131)

摘　　要：目的探讨中期妊娠孕妇血清C反应蛋白（C-reactive protein，CRP）水平与早产的相关性。方法2004年3月-2006年6月采用免疫比浊法测定254例妊娠14-24周孕妇血清CRP值，并观察妊娠结局。结果先兆早产组CRP明显高于对照组（P〈O．001）；保胎失败组CRP明显高于保胎成功组，血清CRP浓度为9．00Mg／L可作为早产的诊断域值。结论CRP水平增高，可作为预测早产的早期监测指标。Objective To investigate the association of C- reactive protein （CRP） with preterm delivery. Method SerLm C- reactive protein values of women in 14-24 gestation weeks were measured with method of immunoturbidimetry, and the outcomes of pregnancy were monitored. Results Serum C - reactive protein level in women with threatened preterm delivery group was significantly higher than that of the control group （P〈 0.00]）, spontaneous delivery group was significantly higher than that of the indicated delivery group, and maternal serum CRP level 9.00mg/L was defined as the threshold vaule of preterm delivery. Conclusions Clinical measurement of serum CRP value may serve as a specific marker in predicting premature delivery.

关 键 词：C反应蛋白 妊娠 早产 

分 类 号：R714.1[医药卫生—妇产科学]