吸毒人员的肝酶类、心肌酶谱九项生化指标分析  

The 9 Items of Biochemical Indexes of Liver and Myocardial Enzymes in Intravenous Drug Abusers

作　　者：王小刚[1] 滕军[2] 李谋喜 杨珂[1] 刘芳[1] 

机构地区：[1]怀化市中医院,湖南怀化418000 [2]怀化市公安局强制戒毒所

出　　处：《实用预防医学》2007年第3期885-886,共2页Practical Preventive Medicine

摘　　要：目的了解吸毒对肝功能、心脏功能的影响,为临床提供依据。方法对某戒毒所静脉吸毒者、非静脉吸毒者及同期某学院的学生健康体检人员血清,用美国杜邦AR全自动生化分析仪检测肝酶类,心肌酶谱,九项生化指标,采用异常例数,异常率进行统计分析。结果静脉吸毒组异常率:ALT52.7%,AST47.3%,GGT15.5%,ALP24.5%,TBA1.8%,CK24.5%,CK-MB15.5%,a-HBD41.8%,与正常对照组比较有统计学意义(P<0.01)。结论静脉吸毒者对肝脏、心肌的损害比非静脉吸毒者更大,因此,有关部门应加强对青少年的法制和健康教育,使之远离毒品,拒绝毒品,保障其身心健康。Objective Effects of drug abuse on liver and heart functions were studied for providing clinical basic information. Methods Serum samples were collected from the intravenous （IV） drug abusers, the non- IV drug abusers, and a group of healthy physical check - up students to perform 9 items of liver and myocardial enzymes and other biochemical parameters by US Dupont analytical reagent automatic analyzer. The numbers and percentages of abnormal cases were used as parameters in statistical analysis. Results The abnormal percentages of the IV drug abusers were ALT52.7%, AST 47.3% ,GGTIS..5% ,ALP24..5% ,TBAI. 8% ,CK24..5% ,CK - MBIS..5% ,and a - HBD41. 8%, and showed highly significant differences as compared with the normal controls （ P〈 0.01 ）. Conclusions The results suggest that the IV drug use has more severe adverse effects on liver and heart functions than those of the non- IV drug use; therefore it is important to educate the adolescents refusing illegal drug abuse for keeping healthy body and mind.

关 键 词：静脉吸毒 肝酶类 肝功损害 心肌酶谱 心肌损害 

分 类 号：R446[医药卫生—诊断学]